Commentary
http://www.recombinomics.com/News/02021 ... ation.html2012 Guizhou H5N1 Recombination and RBD Changes Recombinomics Commentary 21:45
February 2, 2012 The WHO Chinese National Influenza Center has released HA, NA, and MP sequences (at GISAID) from the most recent confirmed H5N1 case (39M) from Guizhou Province in China, A/Guizhou/1/2012, representing the first 2012 human H5N1 sequence. The sample was collected on January 22, 2012, the date of the patient’s death, and the center is commended for the rapid release of these important sequences. Like the December case from Shenzhen, China, A/Guangdong-Shenzhen/1/2011, this cases has no reported contact with poultry. However, unlike the earlier case, which was related to clade 2.3.2.1 sequences frequently reported in wild birds in Hong Kong at this time of year, the Guizhou sequence was most closely related to 2009 environmental samples from Guizhou poultry markets which were
clade 2.3.4.2.
A human case of influenza A(H5N1) virus infection was reported in China. The virus belongs to
, and is expected to be sensitive to NAIs and adamantanes by sequencing. Further analysis of the virus including its antigenic relationship with developed candidate reassortant vaccine viruses is being conducted by the WHO Collaborating Centre for Reference and Research on Influenza at the Chinese Center for Disease Control and Prevention.
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