Rhiza Labs FluTracker Forum

closest human H3:
A/NY/587/1996/11/18
15 years ago - 30 years difference to current H3

closest human N2:
A/Waikato/21/2002/07/01

no new human segments to swine since then (?)

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no patents on genes, publish the GISAID sequences !

Old seasonal story. The closest human are trH3N2 cases.

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www.twitter.com/hniman

they should do a test -at least in mice-
how much the current vaccine protects
against current swinish H3N2

or the old 1996 vax, if they still have it
or the current swine H3-vax

mice,ferrets,pigs

25 years was sufficient to cause another
pandemic-like outbreak in 1977, although it mainly affected
the children and is not usually counted as pandemic.

now we have 30 years (2*15 , mutated since 1996 in swine
and humans away from each other)

_________________
no patents on genes, publish the GISAID sequences !

Testing of a new trH3N2 target, A/Minnesota/11/2011, started weeks ago. You remain in lala land.

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www.twitter.com/hniman

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www.twitter.com/hniman

This study is very concerned with th3n2 as well.


"Conclusions: Human co-infection with pH1N1 and H3N2 resulted in a probable reassortant virus. This could result in emergence of a new subtype with high transmissibility, including pandemic potential. Laboratory-based surveillance including WGS is critical, especially when different subtypes of influenza viruses are co-circulating to allow early detection of reassortants. In-vivo experiments should be conducted to evaluate the fitness, pathogenicity and transmissibility of this reassortment.


http://www.abstractsonline.com/plan/Vie ... 537A439%7d

To Googler #1 responding to Googler #2. The trH3N2 in Washington County has NOTHING to do with current seasonal H3N2. ALL 8 gene segemnts are KNOWN and IDENTICAL. This is SWINE H3N2 in Washington County. Seven genes are trH3n2 and one is pandemic H1N1.

Your post is OFF TOPIC and in la la land.

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www.twitter.com/hniman

EPI335633 A/Indiana/08/2011 (A/H3N2) segment 8 (NS) 27.0 7.001057e+00 14/14 (100%)
EPI335625 A/Pennsylvania/10/2011 (A/H3N2) segment 8 (NS) 27.0 7.001057e+00 14/14 (100%)
EPI335622 A/Pennsylvania/11/2011 (A/H3N2) segment 8 (NS) 27.0 7.001057e+00 14/14 (100%)
EPI333147 A/Indiana/08/2011 (A/H3N2) segment 8 (NS) 27.0 7.001057e+00 14/14 (100%)
EPI273590 A/swine/Nakhon Pathom/2002 (A/H3N2) segment 8 (NS) 27.0 7.001057e+00 14/14 (100%)
EPI272373 A/swine/Chonburi/2002 (A/H3N2) segment 8 (NS) 27.0 7.001057e+00 14/14 (100%)
EPI271842 A/swine/Chachoengsao/2002 (A/H3N2) segment 8 (NS) 27.0 7.001057e+00 14/14 (100%)
EPI235256 A/swine/Chachoengsao/2003 (A/H3N2) segment 8 (NS) 27.0 7.001057e+00 14/14 (100%)

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www.twitter.com/hniman

Note that the above pedigree includes only the three isolates from patients with no swine contact and early swine sequences from Thailand.

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www.twitter.com/hniman

it's still the same HA and NA, although 15 years evolved separately.

Can it cause another pandemic ?
Then the danger from frozen viruses and artificial (terrorists)
reassortants should be really big

_________________
no patents on genes, publish the GISAID sequences !