Rhiza Labs FluTracker Forum

Yes I thought 2008/2009 seasonal H1N1 was gone. Consumed by it's big brother P/H1N1 which has now become the new seasonal H1N1.

2008 H1N1 was 99.9% resistant against Tamiflu.

Maybe Niman could clarify. Thanks

Must be rather galling for Biota shareholders like you that after nearly three years of swine flu there's still only low levels of Tamiflu resistance and you've missed the market for the northern hemisphere this winter.

Commentary

http://www.recombinomics.com/News/02091 ... ables.html

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A few states have reported seasonal H1N1, as have countries in Europe, including Spain, but the number of cases is very low.

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Colorado has reported 2 unsubtypable

http://www.cdphe.state.co.us/dc/Influen ... esults.pdf

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Reported Human Infections with Swine Origin Influenza Viruses (SOIV) in the United States since 2005
As of December 17, 2010, 19 cases of human infection with swine origin influenza viruses (SOIV) have been reported in the United States. These are viruses that normally infect pigs. Like human influenza viruses, there are different subtypes and strains of swine origin influenza viruses. The main swine viruses circulating in U.S. pigs in recent years are swine triple reassortant (tr) H1N1 influenza virus, trH3N2 virus and trH1N2 virus. Of the 19 human cases reported since 2005, 12 have been trH1N1 viruses, six have been trH3N2 viruses and one has been a trH1N2 virus. All 19 persons infected with swine viruses recovered from their illness. Twelve cases occurred in children (persons younger than 19) and 7 cases occurred in adults. In 15 cases, exposure to swine has been identified. Although no person-to-person transmission of swine influenza viruses has been laboratory confirmed in the investigation of these cases to date, some cases reported only exposure to ill persons and no exposure to live pigs. Thus, limited person-to-person is likely to have occurred.

Related Links & Past Reports
December 17, 2010 "Have You Heard"

November 12, 2010 "Have You Heard"

Information about 11 cases occurring between 2005 and 2009 can be found in the New England Journal of Medicine article entitled "Triple-Reassortant Swine Influenza A (H1) in Humans in the United States, 2005–2009" available at
http://www.nejm.org/doi/pdf/10.1056/NEJMoa0903812

http://www.cdc.gov/flu/swineflu/soiv_cases.htm

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Here is Nancy Cox slide presentation o detection of pH1N1 (which is a trH1n1) which is a blueprint for trH3N2, although events on the detection side are MUCH slower

http://www.who.int/csr/disease/influenza/COX3.pdf

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Still no representations for unsubtypables in week 5 FluView, but now H1N1 exceeds H3N2 nationally.

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Week 5 unsubtypable in Guilford County, North Carolina
http://www.epi.state.nc.us/epi/gcdc/flu ... s1011.html

05 2/5/2011 88 Alamance A (H1N1) Pandemic 1
Alamance A (H3) 1
Alamance B 1
Avery A (H3) 1
Beaufort A (H1N1) Pandemic 1
Beaufort A (H3) 1
Bertie A (H1N1) Pandemic 1
Cabarrus B 3
Chatham A (H3) 1
Cumberland A (H3) 1
Duplin B 2
Durham B 1
Forsyth A (H1N1) Pandemic 1
Forsyth B 2
Franklin A (H1N1) Pandemic 3
Franklin B 1
Granville B 1
Guilford A (unsubtypable) 1
Guilford A (H1N1) Pandemic 9
Guilford B 3
Martin A (H1N1) Pandemic 3
Martin B 1
Mecklenburg B 2
Mitchell B 4
Orange A (H1N1) Pandemic 1
Orange B 1
Pender A (H1N1) Pandemic 2
Richmond A (H1N1) Pandemic 3
Rowan A (H1N1) Pandemic 1
Rowan A (H3) 1
Rowan B 11
Stanly A (H1N1) Pandemic 2
Stokes A (H1N1) Pandemic 1
Stokes B 1
Union B 1
Unknown A (H3) 1
Wake A (H1N1) Pandemic 4
Wake A (H3) 2
Wake B 2
Washington A (H3) 1
Watauga A (H1N1) Pandemic 3
Watauga B 2
Wilkes A (H3) 1
Yancey B 1

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http://www.clark.wa.gov/public-health/d ... 021111.pdf

Washington State Dept of Health document

updated their document for what health conditions should be communicated immediately - listed unsubtypable influenza, among others.

[no cases that I know of, just a procedure to follow]