Dingo wrote:
NS1 wrote:
[
The common ground among these sequences and those in the database on either side of them temporally, especially Iran, is the high quantity of polymorphisms that are novel or rare to pH1N1 and that also appear in zoonotic reservoirs, particularly H3N8, H5N1 and H7N7.
Even small genetic adjustments from animal vectors into human infections, especially H3N8, may create variant behaviour. This potential era of zoonotic sub-segment spillover merits as much investigation for severity (in combination) as does the recognised 225G.
Do we have much sequences or data from 1957 or 1968? I'm wondering if the acquisition of these zoonotic changes is a recent thing, or happened with past pandemics and explains the leap in virulence?
is always at work. We estimate that the ebb and flow is much more active during a pandemic era
prior to the Omega form being reached.
JKT recently did some newspaper perusal from the late 1800's to early 1900's and found epizootics reported. Mike Coston profiled that piece well on
Avian Flu Diary. The relationship of animal breakouts and human breakouts is not completely correlated temporally, using only the data available from newspapers.
Dr. Niman will be a more astute professor on 1957 and 1968 than we can be.
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