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 Post subject: Re: Swine H3N2 Pandemic
PostPosted: Wed Nov 17, 2010 9:24 pm 
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niman wrote:
No, D225G in H3N2 isn't as severe as D225G in H1N1.


Why?


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 Post subject: Re: Swine H3N2 Pandemic
PostPosted: Wed Nov 17, 2010 9:32 pm 
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Dingo wrote:
niman wrote:
No, D225G in H3N2 isn't as severe as D225G in H1N1.


Why?

Differences in H3 and H1 backgrounds.

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 Post subject: Re: Swine H3N2 Pandemic
PostPosted: Wed Nov 17, 2010 9:49 pm 
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Commentary

http://www.recombinomics.com/News/11181 ... demic.html

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 Post subject: Re: Swine H3N2 Pandemic
PostPosted: Wed Nov 17, 2010 11:03 pm 
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Joined: Tue Aug 25, 2009 11:01 am
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A few questions, Dr. Niman:

Are you saying that there is likely a pandemic, or that there is definitely a pandemic?

If definitely, are there any indications as to how serious it will be? Can you make any guess as to how many people have been infected to date?

What do you think is going on at the CDC and WHO now?


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 Post subject: Re: Swine H3N2 Pandemic
PostPosted: Wed Nov 17, 2010 11:19 pm 
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Jon Schultz wrote:
A few questions, Dr. Niman:

Are you saying that there is likely a pandemic, or that there is definitely a pandemic?

If definitely, are there any indications as to how serious it will be? Can you make any guess as to how many people have been infected to date?

What do you think is going on at the CDC and WHO now?

I think that trH3N2 is transmitting it humans. However, this transmission may be slow. Surveillance is poor because detection requires sequencing since H3 and N2 are human. I think the number of positives will rise in the next few weeks, and that should signal how efficient the transmission is.

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 Post subject: Re: Swine H3N2 Pandemic
PostPosted: Thu Nov 18, 2010 2:13 am 
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Joined: Sat Jan 30, 2010 2:44 am
Posts: 926
niman wrote:
Dingo wrote:
niman wrote:
No, D225G in H3N2 isn't as severe as D225G in H1N1.


Why?

Differences in H3 and H1 backgrounds.


Thanks


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 Post subject: Re: Swine H3N2 Pandemic
PostPosted: Thu Nov 18, 2010 2:25 pm 
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Location: Pittsburgh, PA USA
H3N2 pandemic discussed tonight at 10 PM EST

http://www.rense.com/about/guests.htm

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 Post subject: Re: Swine H3N2 Pandemic
PostPosted: Thu Nov 18, 2010 6:09 pm 
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Since this novel trH3N2 has an avian PB2 like 2009 H1N1, does that mean it will evade rapid flu tests as readily as H1N1 did? Or Will it be more readily detected?

And, do we know for sure if any of the seasonal H3N2 infections that were reported over this past year were indeed our good ole "seasonal" H3N2 ?

Isn't it unusual for a seasonal influenza to make such an abrupt comeback immediately following a Pandemic? We've been hearing these sporadic H3N2 occurances here and there even in the Summer. I thought that was extremely odd.

If a patient was typed, and the result pointed to Influena A, seasonal H3N2, would anybody do any further sequencing (outside of those few places that do so for surveilance purposes?)

I thought H1N1 flew under the radar... this virus you are talking about will be a total phantom. We don't have the resources to track it, or the money (I'm speaking from a healthcare point of view).

Influenza is learning to evade our testing, our immune response, our vaccines, and NOBODY is treating anything they can't confirm. Clever virus.... :hello:

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 Post subject: Re: Swine H3N2 Pandemic
PostPosted: Thu Nov 18, 2010 6:30 pm 
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Joined: Wed Aug 19, 2009 10:42 am
Posts: 56044
Location: Pittsburgh, PA USA
littlebird wrote:
Since this novel trH3N2 has an avian PB2 like 2009 H1N1, does that mean it will evade rapid flu tests as readily as H1N1 did? Or Will it be more readily detected?

And, do we know for sure if any of the seasonal H3N2 infections that were reported over this past year were indeed our good ole "seasonal" H3N2 ?

Isn't it unusual for a seasonal influenza to make such an abrupt comeback immediately following a Pandemic? We've been hearing these sporadic H3N2 occurances here and there even in the Summer. I thought that was extremely odd.

If a patient was typed, and the result pointed to Influena A, seasonal H3N2, would anybody do any further sequencing (outside of those few places that do so for surveilance purposes?)

I thought H1N1 flew under the radar... this virus you are talking about will be a total phantom. We don't have the resources to track it, or the money (I'm speaking from a healthcare point of view).

Influenza is learning to evade our testing, our immune response, our vaccines, and NOBODY is treating anything they can't confirm. Clever virus.... :hello:

It not only has avian PB2, but it also has HA D225G.

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 Post subject: Re: Swine H3N2 Pandemic
PostPosted: Thu Nov 18, 2010 6:43 pm 
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Joined: Wed Aug 19, 2009 10:42 am
Posts: 56044
Location: Pittsburgh, PA USA
niman wrote:
littlebird wrote:
Since this novel trH3N2 has an avian PB2 like 2009 H1N1, does that mean it will evade rapid flu tests as readily as H1N1 did? Or Will it be more readily detected?

And, do we know for sure if any of the seasonal H3N2 infections that were reported over this past year were indeed our good ole "seasonal" H3N2 ?

Isn't it unusual for a seasonal influenza to make such an abrupt comeback immediately following a Pandemic? We've been hearing these sporadic H3N2 occurances here and there even in the Summer. I thought that was extremely odd.

If a patient was typed, and the result pointed to Influena A, seasonal H3N2, would anybody do any further sequencing (outside of those few places that do so for surveilance purposes?)

I thought H1N1 flew under the radar... this virus you are talking about will be a total phantom. We don't have the resources to track it, or the money (I'm speaking from a healthcare point of view).

Influenza is learning to evade our testing, our immune response, our vaccines, and NOBODY is treating anything they can't confirm. Clever virus.... :hello:

It not only has avian PB2, but it also has HA D225G.

Tomorrow's P&I will be 7.02%, which may be just above the epidemic threshhold even though flu activity is low country-wide. When the virus starts to role, the P&I will be well above the epidemic threshhold.

State agencies are trying to get samples from hospitalized patients with flu-like symptoms and pneumonia.

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