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PostPosted: Tue Mar 16, 2010 6:51 am 
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Location: Pittsburgh, PA USA
Dingo wrote:
Three questions please:

1. Is E627K found in non-pandemic flus in pigs? If so, they could be a reassortment vessel for this to spread widely in humans.

2. From my reading here and Dr Niman's commentaries, I recall that this mutation was regarded as the last and most dangerous missing part of the jigsaw for pandemic swine flu to really take off (ie be both highly contagious and deadly) - is this correct?

3. From the commentary, it's checked for in gene sequences, but has only been found spontaneously in two places previously?

Re #3, I suppose this is little comfort. Every story about a significant mutation starts with the first one or cluster found, I suppose.

There are swine PB2 sequencs with E627K, but thye would be easily distiguished from the avian PB2 in pandemic H1N1 and te article made no mention of reassortment, which would have added multiple changes.
PB2 offers significant advantage in humans, which is why it is in all human flu's.

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Last edited by niman on Tue Mar 16, 2010 7:44 am, edited 1 time in total.

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PostPosted: Tue Mar 16, 2010 7:15 am 
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Anybody know where Pune is?

Any Baxter facilities nearby?


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PostPosted: Tue Mar 16, 2010 7:17 am 
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SteveMartin wrote:
Anybody know where Pune is?

Any Baxter facilities nearby?

Please.

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PostPosted: Tue Mar 16, 2010 7:43 am 
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niman wrote:
there are swine PB2 sequencs with E627K, but thye would be easily distiguished from the avian PB2 in pandemic H1N1 and te article made no mention of reassortment, which would have added multiple changes.
PB2 offers significant advantage in humans, which is why it is in all humna flu's.


Thanks


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PostPosted: Tue Mar 16, 2010 7:52 am 
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SteveMartin wrote:
Anybody know where Pune is?

Any Baxter facilities nearby?


I do and thanks for your important post.

After some searching, I've found Baxter facilities in Pune, in Mexico adjacent to a major piggery, in Japan where Tamiflu resistance was found, in many areas of Ukraine where D225G was found (and not surprisingly in Norway and Greece too), across the US midwest where swine low reactors was found and they rent key buildings to the WHO and the CDC.

Thank you for opening my eyes to this Baxter conspiracy.


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PostPosted: Tue Mar 16, 2010 7:57 am 
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Uh huh...


H1N1 shots from next week The Times of India 2010-03-03
NEW DELHI: Mass vaccination against the deadly H1N1 swine flu virus are likely to begin in India next week. The 1.5 million doses of vaccines imported by the government from Sanofi Pasteur have passed the safety test. The French vaccine manufacturers submitted the results of their clinical bridge study -- conducted in Delhi and Pune on 100 adult subjects -- to the Drug Controller General of India on Wednesday. The trials were completed on February 21. The results were then checked thoroughly in Lyon before being...

http://article.wn.com/view/2010/03/03/H ... next_week/


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PostPosted: Tue Mar 16, 2010 7:59 am 
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Location: Pittsburgh, PA USA
Dingo wrote:
SteveMartin wrote:
Anybody know where Pune is?

Any Baxter facilities nearby?


I do and thanks for your important post.

After some searching, I've found Baxter facilities in Pune, in Mexico adjacent to a major piggery, in Japan where Tamiflu resistance was found, in many areas of Ukraine where D225G was found (and not surprisingly in Norway and Greece too), across the US midwest where swine low reactors was found and they rent key buildings to the WHO and the CDC.

Thank you for opening my eyes to this Baxter conspiracy.

Please limit Baxter wackdoodle to the conspiracy thread.

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PostPosted: Tue Mar 16, 2010 8:03 am 
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niman wrote:
Please limit Baxter wackdoodle to the conspiracy thread.


Obviously I was joking. :D

Sadly SteveMartin was not.


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PostPosted: Tue Mar 16, 2010 8:12 am 
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I assume you are right that this is E627K, but that is partially because of your remarkable track record. Are there any other PB2 changes that it could be from the description?


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PostPosted: Tue Mar 16, 2010 8:18 am 
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Location: Pittsburgh, PA USA
Dingo wrote:
niman wrote:
Please limit Baxter wackdoodle to the conspiracy thread.


Obviously I was joking. :D

Sadly SteveMartin was not.

Thanks for the clarification.

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