http://www.smittskyddsinstitutet.se/nyainfluensan/Weekly update from Swedish Health Institute for week 45.
The new influenza A (H1N1) in Sweden
Total in Sweden, 6536 laboratory confirmed cases of novel influenza reported.
During week 46 new cases were notified in 2403 compared to 1 233 during the week beginning 45th. The largest number of cases per 100 000 people are now reported from central Sweden with Värmland in the lead. Northern counties remained at a high level.Again, it is among the school children who diagnoses increased the most, and secondly, among the younger children.
Hospitalization have been reported for 167 patients with week 46 age division:
• Over 5 years: 20 people
• 5-14 years: 17 people
• 15-39 years: 68 people• 40-65 years: 54 people • Over 65 years: 8 people
. Overall, the hospital designated for 570 people in the country,
and of them ECMO or mechanical ventilation set for 20th Compared with the distribution of the total, the share of between 40 and 54 increased slightly during the week beginning 46th The reporting of hospital care is probably still not quite complete.
Two deaths were reported weeks 46th Sentinel reporting on the proportion of influenza-like illness among patients seeking general medical practitioner indicates that 155/11 408 (1.4%) reported patient visits have been suspected influenza weeks 46th The largest share, more than 4%, the sentinel physicians in Västerbotten, Värmland and Uppsala reported. The number of searches on Vårdguiden gave a curve to date well follow Sentinel curve.
In the population-based reporting in Stockholm, "Sickness Report", the number of respiratory infections, and influence-like illness in the age groups 0-14 years and 15-39 years. Based on the Hospital Report and data from sentinel sampling, we estimate that between 30 000 and 70 000 people may have fallen ill with flu-country in week 46 and that between 180 000 and 460 000 people in the country may have had the flu for weeks 38th
The development, based not least on the experience of northern counties, suggesting that we will see an increase in the number of cases or a stationary high total in the country over the next few weeks, but vaccination will affect the development and have an accurate projection can not be done.
To SMI has received 20 samples from 13 severely ill patients for further characterization. Samples from 8 ECMO-nursed, 2 respiratory value, 1 st from IVA no indication of respiratory support, and from 2 pc death). Of these, five samples as low concentration of virus that no analysis could be performed. We have the remaining sequence led three of the 8 different gensegment of influenza A (H1N1); neuraminidasgenen (8), NS1 gene (10 pc) and hämagglutiningenen (8). All characterized strains are sensitive to neuraminidase inhibitors (Tamiflu and Relenza) and none have mutations in the NS1, which induces increased virulence. All strains show a great similarity with the vaccine strain (A/California/07/2009) and no common mutations that can make binding to receptor cells in the lungs more efficient could be detected.