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PostPosted: Wed Apr 17, 2013 10:29 am 
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niman wrote:
Gregory Härtl ‏@HaertlG 4m
We are exploring the possibility that #H7N9 can be spread between people; as yet there is no evidence of sustained H2H transmission.

Previously WHO tweets just claimed to H2H

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PostPosted: Wed Apr 17, 2013 10:57 am 
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Gregory Härtl ‏@HaertlG 6m
There are some #H7N9 laboratory-confirmed cases who have no history of contact with poultry, therefore argues for a wide investigation net.

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PostPosted: Wed Apr 17, 2013 10:58 am 
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Given the numbers being publicly disseminated, we can now pretty safely assume that the virus is more prevalent in humans than in avian species. If this was NOT the case, WHO and CDCD would be constantly harping on that fact. Alarm bells have yet to start ringing outside of the bug world, this is pretty surprising considering the Western media's obsession with sensationalizing everything, and popular culture's recent affinity for fictionalized pandemics.


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PostPosted: Wed Apr 17, 2013 11:01 am 
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meteorjosh wrote:
Given the numbers being publicly disseminated, we can now pretty safely assume that the virus is more prevalent in humans than in avian species. If this was NOT the case, WHO and CDCD would be constantly harping on that fact. Alarm bells have yet to start ringing outside of the bug world, this is pretty surprising considering the Western media's obsession with sensationalizing everything, and popular culture's recent affinity for fictionalized pandemics.

When China indirectly confirmed the cluster in the family in the Minhang District in Shanghai as well as 6 cases at the hospital, the jig was up. They could no longer maintain the charade.

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PostPosted: Wed Apr 17, 2013 11:09 am 
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Yes, you definitely hit a credibility wall when you have 40 birds with a virus and 85 humans, yet maintain the position that only contact with birds can make one ill. Of course, the real numbers are no doubt magnitudes higher among both.


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PostPosted: Wed Apr 17, 2013 11:10 am 
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WHO ‏@WHO 24m
To date, WHO has been notified of 82 #H7N9 laboratory-confirmed cases, including 17 fatalities. #influenza #flu
Retweeted by Gregory Härtl

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PostPosted: Wed Apr 17, 2013 11:12 am 
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meteorjosh wrote:
Yes, you definitely hit a credibility wall when you have 40 birds with a virus and 85 humans, yet maintain the position that only contact with birds can make one ill. Of course, the real numbers are no doubt magnitudes higher among both.

Especially when you have to run 47,801 tests to get the 39 H7N9 positives in birds.

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PostPosted: Wed Apr 17, 2013 2:40 pm 
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Minhang H7N9 familial cluster confirmed.

http://www.chinadaily.com.cn/china/2013 ... 416968.htm

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PostPosted: Wed Apr 17, 2013 2:41 pm 
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niman wrote:
Minhang H7N9 familial cluster confirmed.

http://www.chinadaily.com.cn/china/2013 ... 416968.htm

Thread on confirmation

viewtopic.php?f=5&t=9387

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PostPosted: Thu Apr 25, 2013 12:24 am 
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One family cluster was identified with two confirmed and one suspected H7N9 cases.
The confirmed cases were a 69-year-old man and his father, an 87-year-old retired
man, a resident of Shanghai City. The suspected case, aged 57 years, was the first ill
person in the household and developed high fever (maximum temperature 41 ºC),
cough, sputum production, chills and nausea on Feb 11th (Figure 2). After the
suspected case became ill, his brother (confirmed case 1) and the father (confirmed
case 2) had close contact with him, including eating together, providing care, and
accompanying him to seek medical care before his hospitalization. The suspected case
was hospitalized on Feb 20th, diagnosed with pneumonia, placed on mechanical
ventilation and isolated in an ICU the next day. He died of ARDS and multi-organ
failure on Feb 28th. The throat swab collected from him on Feb 26th tested negative for
H7N9, and no specimens were available for H7N9 testing because of his death.
Before his isolation in the hospital, the two confirmed cases had close contact with
him without use of any personal protective equipment. Confirmed case 1 developed
fever (40 ºC), cough, sputum production, nausea and vomiting on Feb 19th, was
admitted to hospital on Feb 25th with a diagnosis of pneumonia, and was isolated the
next day. A throat swab collected from him on Feb 26
th tested negative for H7N9. He
improved and was discharged on Mar 13th. Paired serum specimens collected 7 and 46
days after illness onset were tested by turkey red blood cell hemagglutinin inhibition
assay and demonstrated a four-fold rise in antibody titer (HAI titer <10 and 80,
respectively), indicative of serological confirmation of H7N9 virus infection. The 8
87-year old father (confirmed case 2) developed cough and sputum production on Feb
19th and had high fever (40.2 ºC) on Feb 24th, was admitted to hospital on Feb 25th
with a diagnosis of pneumonia, and isolated the next day. A throat swab collected on
Feb 26th tested positive for H7N9 virus. He died on Mar 4th. The suspected case and
his father (confirmed case 2) lived together and the brother (confirmed case 1) lived
with his wife nearby. All three cases did not raise poultry or other animals, and did not
bring live poultry into their home. None of the three cases in this family cluster had
any direct contact with sick or dead poultry. The suspected case had visited a live
poultry market, purchased a well-appearing chicken, observed the slaughtering
process, brought the freshly killed chicken home, prepared, cooked and ate the
chicken within 2 weeks before his illness onset, but the exact exposure date was
unclear because he was severely ill and died before he could be interviewed.

http://www.nejm.org/doi/suppl/10.1056/N ... pendix.pdf

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