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niman
PostPosted: Thu May 17, 2012 7:57 pm 
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The CDC has released another series of H1N1 sequences, which demonstrates clonal expansion of Tamiflu resistance (H274Y) to California and Illinois (from Texas and Mexico).

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niman
PostPosted: Thu May 17, 2012 8:02 pm 
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Recent H274Y

EPI370418 A/Texas/35/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI370415 A/Texas/24/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI370412 A/Illinois/01/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI370409 A/Illinois/01/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI370394 A/Texas/31/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI370391 A/Texas/34/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI370388 A/Texas/33/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI370385 A/California/21/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI370267 A/PERTH/33/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI368654 A/Texas/30/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI368650 A/Texas/29/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI368642 A/Texas/26/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI366336 A/Texas/24/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI366333 A/Texas/23/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI366331 A/Texas/23/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI366310 A/Puerto Rico/09/2011 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI366298 A/Mexico/689/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI366295 A/Mexico/2440/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI366289 A/Mexico/1818/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)
EPI366286 A/Mexico/1474/2012 (A/H1N1 pdm09) segment 6 (NA) 27.0 8.182548e+00 14/14 (100%)

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niman
PostPosted: Thu May 17, 2012 8:07 pm 
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Identical NA sequences:

EPI370415 A/Texas/24/2012 (A/H1N1 pdm09) segment 6 (NA) 2604.9 0.000000e+00 1410/1410 (100%)
EPI370412 A/Illinois/01/2012 (A/H1N1 pdm09) segment 6 (NA) 2604.9 0.000000e+00 1410/1410 (100%)
EPI370409 A/Illinois/01/2012 (A/H1N1 pdm09) segment 6 (NA) 2604.9 0.000000e+00 1410/1410 (100%)
EPI368650 A/Texas/29/2012 (A/H1N1 pdm09) segment 6 (NA) 2604.9 0.000000e+00 1410/1410 (100%)
EPI366336 A/Texas/24/2012 (A/H1N1 pdm09) segment 6 (NA) 2604.9 0.000000e+00 1410/1410 (100%)
EPI366333 A/Texas/23/2012 (A/H1N1 pdm09) segment 6 (NA) 2604.9 0.000000e+00 1410/1410 (100%)
EPI366331 A/Texas/23/2012 (A/H1N1 pdm09) segment 6 (NA) 2604.9 0.000000e+00 1410/1410 (100%)
EPI366295 A/Mexico/2440/2012 (A/H1N1 pdm09) segment 6 (NA) 2604.9 0.000000e+00 1410/1410 (100%)
EPI366289 A/Mexico/1818/2012 (A/H1N1 pdm09) segment 6 (NA) 2604.9 0.000000e+00 1410/1410 (100%)

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niman
PostPosted: Thu May 17, 2012 8:16 pm 
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Top California NA matches (all have H274Y)

EPI370385 A/California/21/2012 (A/H1N1 pdm09) segment 6 (NA) 2604.9 0.000000e+00 1410/1410 (100%)
EPI370415 A/Texas/24/2012 (A/H1N1 pdm09) segment 6 (NA) 2588.3 0.000000e+00 1407/1410 (99%)
EPI370412 A/Illinois/01/2012 (A/H1N1 pdm09) segment 6 (NA) 2588.3 0.000000e+00 1407/1410 (99%)
EPI370409 A/Illinois/01/2012 (A/H1N1 pdm09) segment 6 (NA) 2588.3 0.000000e+00 1407/1410 (99%)
EPI368650 A/Texas/29/2012 (A/H1N1 pdm09) segment 6 (NA) 2588.3 0.000000e+00 1407/1410 (99%)
EPI366336 A/Texas/24/2012 (A/H1N1 pdm09) segment 6 (NA) 2588.3 0.000000e+00 1407/1410 (99%)
EPI366333 A/Texas/23/2012 (A/H1N1 pdm09) segment 6 (NA) 2588.3 0.000000e+00 1407/1410 (99%)
EPI366331 A/Texas/23/2012 (A/H1N1 pdm09) segment 6 (NA) 2588.3 0.000000e+00 1407/1410 (99%)
EPI366295 A/Mexico/2440/2012 (A/H1N1 pdm09) segment 6 (NA) 2588.3 0.000000e+00 1407/1410 (99%)
EPI366289 A/Mexico/1818/2012 (A/H1N1 pdm09) segment 6 (NA) 2588.3 0.000000e+00 1407/1410 (99%)

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niman
PostPosted: Thu May 17, 2012 8:37 pm 
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All March 2012 Texas isolates have H274Y.

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niman
PostPosted: Thu May 17, 2012 9:36 pm 
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Thursday at 10 PM EDT

http://www.rense.com/about/guests.htm

Interview will cover spreading Tamiflu resistance in Texas and Mexico (and now California and Illinois) as well as H5N1 transmission, including A242T/S.

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niman
PostPosted: Fri May 18, 2012 5:40 am 
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niman wrote:
The CDC has released another series of H1N1 sequences, which demonstrates clonal expansion of Tamiflu resistance (H274Y) to California and Illinois (from Texas and Mexico).

Discussed at beginning of interview

http://rense.gsradio.net:8080/rense/spe ... 051712.mp3

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niman
PostPosted: Fri May 18, 2012 1:22 pm 
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Commentary

http://www.recombinomics.com/News/05181 ... CA_IL.html

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niman
PostPosted: Fri Jun 01, 2012 6:55 pm 
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Same sequences in Maryland and New York

viewtopic.php?f=5&t=8099

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niman
PostPosted: Tue Jun 19, 2012 10:57 am 
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Thread on DoD match in California

viewtopic.php?f=5&t=8117

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