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PostPosted: Mon Nov 07, 2011 7:47 pm 
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Phylogenetic analysis does not support infection of the 29F (A/Indonesia/NIHRD11815/2011) by either of the two children (5F - A/Indonesia/NIHRD11766/2011 or 10M - A/Indonesia/NIHRD11771/2011).

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PostPosted: Mon Nov 07, 2011 8:13 pm 
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niman wrote:
Phylogenetic analysis does not support infection of the 29F (A/Indonesia/NIHRD11815/2011) by either of the two children (5F - A/Indonesia/NIHRD11766/2011 or 10M - A/Indonesia/NIHRD11771/2011).

26 October 2011 -The Ministry of Health of Indonesia has announced two new confirmed cases of human infection with avian influenza A(H5N1) virus.

The first case is a 5-year old female from Bangli district, Bali Province. She developed symptoms on 27 September, and was first admitted to a local general hospital on 5 October. She died on 9 October.

The second case is a 10-year old male, the brother of the first case. He developed symptoms on 30 September, and was first admitted to the hospital on the same day as his sister. He died on 10 October.

An epidemiological investigation conducted by the Ministry of Health and local health officers indicated that the children lived in an area with poultry, and household and neighborhood poultry had died prior to the children’s illnesses.

Laboratory tests have confirmed infection with avian influenza A(H5N1) virus.

Of the 181 cases confirmed to date in Indonesia, 149 have been fatal.

http://www.who.int/csr/don/2011_10_26/en/index.html

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PostPosted: Mon Nov 07, 2011 8:41 pm 
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niman wrote:
Phylogenetic analysis does not support infection of the 29M (A/Indonesia/NIHRD11815/2011) by either of the two children (5F - A/Indonesia/NIHRD11766/2011 or 10M - A/Indonesia/NIHRD11771/2011).

However, although the source is not the same, all three have the same three RBD changes (D188N, A189G, R193M)

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PostPosted: Mon Nov 07, 2011 8:52 pm 
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niman wrote:
niman wrote:
Phylogenetic analysis does not support infection of the 29F (A/Indonesia/NIHRD11815/2011) by either of the two children (5F - A/Indonesia/NIHRD11766/2011 or 10M - A/Indonesia/NIHRD11771/2011).

However, although the source is not the same, all three have the same three RBD changes (D188N, A189G, R193M)

All three Bali sequences also had V-7T, A-3S, S167T, and V178I.

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PostPosted: Tue Nov 08, 2011 9:19 am 
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niman wrote:
Phylogenetic analysis does not support infection of the 29F (A/Indonesia/NIHRD11815/2011) by either of the two children (5F - A/Indonesia/NIHRD11766/2011 or 10M - A/Indonesia/NIHRD11771/2011).

Further analysis identfies recombination within the Bali sequences. this will be discussed on a new thread

viewtopic.php?f=5&t=7693

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