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PostPosted: Sat Sep 03, 2011 5:34 am 
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niman wrote:
niman wrote:
CDC has linked MMWR early release to its SOIV website

http://www.cdc.gov/flu/swineflu/soiv_cases.htm

The updated CDC site has strategically ignored the MMWR report on the Minnesota cluster

Reported Human Infections with Swine Origin Influenza Viruses (SOIV) in the United States since 2005
As of January 25, 2011, 20 cases of human infection with swine origin influenza viruses (SOIV) have been reported in the United States. These are viruses that normally infect pigs. Like human influenza viruses, there are different subtypes and strains of swine origin influenza viruses. The main swine viruses circulating in U.S. pigs in recent years are swine triple reassortant (tr) H1N1 influenza virus, trH3N2 virus and trH1N2 virus. Of the 20 human cases reported since 2005, 12 have been trH1N1 viruses, seven have been trH3N2 viruses and one has been a trH1N2 virus. All 20 persons infected with swine viruses recovered from their illness. Thirteen cases occurred in children (persons younger than 19) and 7 cases occurred in adults. In 16 cases, direct or indirect exposure to swine prior to onset of illness has been identified. Although no person-to-person transmission of swine influenza viruses has been laboratory confirmed in the investigation of these cases to date, some cases reported only exposure to ill persons and no exposure to live pigs. Thus, limited person-to-person is likely to have occurred.

Related Links & Past Reports
Swine-Origin Influenza A (H3N2) Virus Infection in Two Children — Indiana and Pennsylvania, July — August 2011. MMWR 2011; 60 (Early Release); 1-4.
Update: Influenza Activity — United States, October 3, 2010-February 5, 2011. MMWR 2011; 60(06):175-181
Update: Influenza Activity — United States, October 3, 2010-December 11, 2010. MMWR 2010; 59(50):1651-1655
December 17, 2010 “Have You Heard”
November 12, 2010 “Have You Heard”
Information about 11 cases occurring between 2005 and 2009 can be found in the New England Journal of Medicine article entitled “Triple-Reassortant Swine Influenza A (H1) in Humans in the United States, 2005–2009” [262 KB, 10 pages]

CDC hiding of Minnesota cluster is being discussed here

viewtopic.php?f=5&t=7459

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PostPosted: Sat Sep 03, 2011 6:23 am 
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A report released on Friday by the U.S. Centers for Disease Control and Prevention serves as a reminder that pigs can be “mixing vessels” for new flu viruses. Two young children became infected with new versions of flu – luckily, strains that were not especially harmful -- and both recovered.

Both cases are linked to summer agricultural fairs, where swine and other animals are on display and often petted by adults and children, CDC and state health officials said.

What’s unusual about both cases is the type of changes in the virus. Flu viruses have eight genes, and this one is seven-eighths pig virus – a virus designated H3N2 that’s been circulating among swine for years. But one single gene comes from the H1N1 swine flu virus that caused a new pandemic of influenza in 2009 and which is now part of the human seasonal flu mix.

“Although reassortment between swine influenza and 2009 influenza A (H1N1) viruses has been reported in pigs in the United States, this particular genetic combination of swine influenza virus segments is unique and has not been reported previously in either swine or humans,” Scott Epperson at the CDC, along with colleagues there and in Indiana, wrote in the report. “Because these viruses carry a unique combination of genes, no information currently is available regarding the capacity of this virus to transmit efficiently in swine, humans, or between swine and humans.”

Reassortment is a process different from mutation, one in which viruses swap genes or even longer stretches of genetic material. The H1N1 swine flu virus was the result of this kind of swap-out -- a mixture of human, bird and pig viruses that also, luckily, turned out not to be especially deadly although it did at first strike younger, healthier people than are usually made seriously ill by flu.

While the flu vaccine does not protect against a new virus coming straight from pigs to people, the virus can be treated with the two drugs that work against seasonal flu – Tamiflu and Relenza.

But this virus doesn’t look especially dangerous, said CDC flu experts Dr. Lyn Finelli and Dr. Michael Shaw. Both children, under 5, are fine. “They recovered completely and they had very mild illnesses,” Finelli said. “It’s not scary. It is typical of what we see during county fair and agricultural fair season. We always see a few cases of these swine flu reassortants.”

Both children had potential direct or indirect exposure to pigs, Finelli said. One, a girl in Indiana, was cared for by a woman who exhibited pigs at a fair. It’s possible the caregiver had an infection she did not even notice and gave it to the child. The other case, a boy in Pennsylvania, visited a fair where there was a petting zoo and pigs on show.

Finelli said public health labs had the money they need to test for new flu viruses. CDC was urging doctors to keep an eye out for unusual types of flu and to ask patients with flu-like symptoms if they have been to a fair or been around pigs.

Pigs can catch human flu easily, and vice-versa. Shaw noted that pigs were more likely to catch H1N1 from people than the other way around.

http://www.nationaljournal.com/healthca ... e-20110902

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PostPosted: Sat Sep 03, 2011 6:27 am 
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Health officials say a novel strain of swine flu has sickened two children in Pennsylvania and Indiana.

One had contact with pigs. The other is believed to have been infected by a caregiver who had contact with pigs, suggesting the virus can spread person-to-person.

The Centers for Disease Control and Prevention says the new virus contains a gene from the H1N1 swine flu that caused a worldwide scare two years ago, plus parts of other viruses that have infected pigs over the last decade.

The children were infected in July and August and have recovered. Both had received flu shots last year.

Officials are investigating other reports of illness in people who attended an agricultural fair in Pennsylvania. No additional cases have been confirmed so far.

http://www.cbsnews.com/stories/2011/09/ ... 1127.shtml

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PostPosted: Sat Sep 03, 2011 6:48 am 
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By Jo Ciavaglia Staff writer | 3 comments


Federal and state health officials say a new swine flu strain recently sickened two preschool age children in Pennsylvania and Indiana, but they cautioned the cases appear to be isolated.

The new virus contains a gene from the H1N1 swine flu, which caused a global pandemic two years ago, and parts of other previous, rare swine flu viruses called H3N2, according to the Centers for Disease Control and Prevention, which included the two cases in a Morbidity and Mortality Weekly Report, issued online Friday.



Both the infected children, ages 2 and 5, had direct or indirect contact with pigs prior to becoming sick, according to the CDC. Both children have recovered and each received a seasonal flu shot last year that contained protection against H1N1.

No additional cases have been confirmed as of Friday.

Scientists found no specific link between the two cases and there is no immediate evidence of sustained human-to-human transmission, the CDC said.

"At this time, with only one case of this kind identified in Pennsylvania, we cannot yet say there is a significant risk to public health," said Pennsylvania Department of Health Secretary Dr. Eli Avila. "However, it is something that we are taking very seriously and actively investigating."

The Pennsylvania Department of Health on Friday issued an advisory urging the public take precautions to prevent the spread of respiratory viruses in light of its investigation into the new swine flu strain. The agency is urging public health professionals to watch for patients with flu-like symptoms and forward lab samples to the state if a patient tests positive for Type-A virus.

State health officials are conducting exposure investigations in Schuylkill and Washington counties among people who attended an agricultural fair.

The most recent case reported appeared in a 2-year-old Schuylkill County girl who attended the fair and had contact with pigs. She became sick on Aug. 20 with a high fever, dry cough and lethargy. She tested positive for Type-A flu at a local hospital emergency room, but was not admitted.

The samples were sent to the state health labs and CDC for further testing, which confirmed the unique strain, which resembles a strain found in an Indiana boy in July. The boy, who has chronic health conditions, reportedly did not have direct exposure to pigs, but one of his caretakers did before the boy became ill.

Bucks County Health Department Director Dr. David Damsker says the discovery of a new flu strain is not unusual, particularly given the CDC's new national surveillance effort designed to identify new flu strains and track flu virus trends.

"We're starting to see more strains that may not have been noticed 20 years ago because we're looking so closely today," Damsker said.

Influenza viruses are commonly found in humans, swine, birds and other animals and there are more than 50 strains of human flu virus alone. Seasonal flu season typically runs December through March.

Each winter, scientists try to predict which flu strains will circulate so they can develop an effective vaccine for the following season. Three strains are picked, two from the Type A family of influenza and one from Type B, but there is no way to predict with 100-percent accuracy which flu strains will be more active each year.

Every year public health officials typically see a few flu strains the seasonal vaccine does not protect against, Damsker said, adding that, based on the two confirmed cases, the new swine strain does not appear any more dangerous than regular flu.

"At this point, we don't think it's anything to be concerned about," he added.

http://www.phillyburbs.com/news/local/c ... a9a2d.html

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PostPosted: Sat Sep 03, 2011 6:53 am 
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niman wrote:
By Jo Ciavaglia Staff writer | 3 comments



State health officials are conducting exposure investigations in Schuylkill and Washington counties among people who attended an agricultural fair.

The most recent case reported appeared in a 2-year-old Schuylkill County girl who attended the fair and had contact with pigs. She became sick on Aug. 20 with a high fever, dry cough and lethargy. She tested positive for Type-A flu at a local hospital emergency room, but was not admitted.


http://www.phillyburbs.com/news/local/c ... a9a2d.html

Plot thickening.

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PostPosted: Sat Sep 03, 2011 6:58 am 
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niman wrote:
niman wrote:
By Jo Ciavaglia Staff writer | 3 comments



State health officials are conducting exposure investigations in Schuylkill and Washington counties among people who attended an agricultural fair.

The most recent case reported appeared in a 2-year-old Schuylkill County girl who attended the fair and had contact with pigs. She became sick on Aug. 20 with a high fever, dry cough and lethargy. She tested positive for Type-A flu at a local hospital emergency room, but was not admitted.


http://www.phillyburbs.com/news/local/c ... a9a2d.html

Plot thickening.

http://www.washingtonfair.org/

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PostPosted: Sat Sep 03, 2011 7:02 am 
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Location: Pittsburgh, PA USA
niman wrote:
niman wrote:
niman wrote:
By Jo Ciavaglia Staff writer | 3 comments



State health officials are conducting exposure investigations in Schuylkill and Washington counties among people who attended an agricultural fair.

The most recent case reported appeared in a 2-year-old Schuylkill County girl who attended the fair and had contact with pigs. She became sick on Aug. 20 with a high fever, dry cough and lethargy. She tested positive for Type-A flu at a local hospital emergency room, but was not admitted.


http://www.phillyburbs.com/news/local/c ... a9a2d.html

Plot thickening.

http://www.washingtonfair.org/

Monday, August 15 - UPMC for Life - “62” & Over Free Till 4 p.m.



Time
Event
Location


9:00 a.m.
Tractor Driving Contest
Parking Lot


9:00 a.m.
Open Rabbit Show



10:00 a.m.
Harness Racing
GS


11:00 a.m.
Spinning Contest in Wool Room



11:00 a.m.
Senior Citizens Activities
ST


Noon
Breeding Hog Show
SA


1:00 p.m.
Kitchen Band
ST


2:00 p.m.
Donnie Cameron
SA


3:00 p.m.
Dance Extensions PAC
ST


4:00 p.m.
Market Hog Show
SA


5:00 p.m.
Mon Valley Cloggers
ST


7:00 p.m.
Pro Stock Tractors / Hot Semis
GS


7:00 p.m.
Donnie Cameron
ST



Tuesday, August 16 - Log Cabin Fence Day - Special Discount Admission - $6.00



Time
Event
Location


8:30 a.m.
Junior Rabbit Show
SA


9:00 a.m.
4-H Meat Rabbit Pens
SA


9:00 a.m.
Poultry Show & Showmanship



9:00 a.m.
Beef Cattle Open & Junior
SA


10:00 a.m.
Harness Racing
GS


2:00 p.m.
Prospect Steer & Heifer Show
SA


6:00 p.m.
Market Steer Show
SA


7:00 p.m.
Monster Trucks
GS


8:00 p.m.
Karaoke - Dave McMurdy
ST



Wednesday, August 17



Time
Event
Location


8:00 a.m.
Light Horse & Pony Halter Classes
SA


9:30 a.m.
Junior Dairy Clipping
SA


10:00 a.m.
4-H Modeling Contest
ST


11:00 a.m.
4-H & FFA Dairy Showmanship & Fitting
SA


1:00 p.m.
Under 8 Kiddie Dairy Showmanship
SA


4:00 p.m.
Cheerleading
GS


5:00 p.m.
Market Lambs
SA


6:00 p.m.
Senior High Bands
GS


8:00 p.m.
School Bus Demolition Derby
GS


8:00 p.m.
Classic Rock Band - Refuge
ST


Thursday, August 18


Time
Event
Location


8:00 a.m.
Breeding Sheep Open & Junior
SA


9:00 a.m.
4-H Horse & Pony Show
GS


9:00 a.m.
Dairy Show
SA


2:00 p.m.
Lead Line Contest
SA


6:00 p.m.
4-H Benefit Auction
ST


7:00 p.m.
Painted Pony Rodeo - Laser Show
GS


7:00 p.m.
Farmers Madness & Milk Chugging
SA


8:00 p.m.
Karaoke - Dave McMurdy
ST



Friday, August 19 - Children - 12 & Under Free Till 4 p.m.


Time
Event
Location


9:00 a.m.
4-H Horse & Pony Show
GS


9:00 a.m.
Dairy Goat Show
SA


1:00 p.m.
Animals on Hoof Dressing Contest
SA


3:00 p.m.
Grace Christian Dance
ST


4:00 p.m.
North Star Kids
ST


5:00 p.m.
Radio Disney
ST


7:00 p.m.
Tap N Toes and All That Jazz
ST


7:00 p.m.
Market Livestock Sale - Rabbits & Goats
SA


7:00 p.m.
Street Stock Truck & Mini Modified Tractors
GS


8:30 p.m.
Magician Bill Horner
ST


Saturday, August 20 - Waste Management Day


Time
Event
Location


9:00 a.m.
Farm Tractor Pull
GS


10:00 a.m.
Market Livestock Sale - Hogs, Lambs & Steers
SA


11:00 a.m.
Artisans in Action
ST


Noon
Backroads Bluegrass
ST


1:00 p.m.
Mid-Life Crisis
ST


2:00 p.m.
Bits n’ Pieces
ST


6:00 p.m.
Demolition Derby - Outhouse Races Between Heats
GS


7:00 p.m.
Amanda Stoneking
ST


8:00 p.m.
Country Band - Saddle Up
ST

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PostPosted: Sat Sep 03, 2011 8:27 am 
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Commentary

http://www.recombinomics.com/News/09031 ... _Wash.html

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PostPosted: Sat Sep 03, 2011 12:47 pm 
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Commentary

http://www.recombinomics.com/News/09031 ... N_CDC.html

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PostPosted: Sat Sep 03, 2011 3:08 pm 
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Role of M gene of H1N1 in transmission and acquisition by trH3N2 discussed here

viewtopic.php?f=5&t=7460&start=3

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