Rhiza Labs FluTracker Forum

22 sets of H1N1 were released at Genbank by the Central Research Institute for Epidemiology in Moscow. 17 of the 22 HA sequences had S188T and most (12/22) sequences had D225G (4), D225N (3), or both (5). Most or all of these sequences were from autopsy lung.

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LOCUS JN185107 1701 bp cRNA linear VRL 01-SEP-2011
DEFINITION Influenza A virus (A/Nizhnii Novgorod/CRIE-UBA/2011(H1N1)) segment
4 hemagglutinin (HA) gene, complete cds.
ACCESSION JN185107
VERSION JN185107.1 GI:339518896
DBLINK Project: 37813
KEYWORDS .
SOURCE Influenza A virus (A/Nizhnii Novgorod/CRIE-UBA/2011(H1N1))
ORGANISM Influenza A virus (A/Nizhnii Novgorod/CRIE-UBA/2011(H1N1))
Viruses; ssRNA negative-strand viruses; Orthomyxoviridae;
Influenzavirus A.
REFERENCE 1 (bases 1 to 1701)
AUTHORS Yatsyshina,S., Minenko,A., Braslavskaya,S., Kudryavtseva,A. and
Shipulin,G.
TITLE Molecular characterisation of Influenza virus A/H1N1v in Russia in
2011
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1701)
AUTHORS Yatsyshina,S., Minenko,A., Braslavskaya,S., Kudryavtseva,A. and
Shipulin,G.
TITLE Direct Submission
JOURNAL Submitted (27-JUN-2011) Federal Budget Institute of Science,
Central Research Institute for Epidemiology, 3A, Novogireevskaya,
Moscow 111123, Russia
FEATURES Location/Qualifiers
source 1..1701
/organism="Influenza A virus (A/Nizhnii
Novgorod/CRIE-UBA/2011(H1N1))"
/mol_type="viral cRNA"
/strain="A/Nizhnii Novgorod/CRIE-UBA/2011"
/serotype="H1N1"
/isolation_source="autopsy lung tissue"
/host="Homo sapiens"
/db_xref="taxon:1050890"
/segment="4"
/country="Russia"
/collection_date="23-Jan-2011"
/note="lineage: swl"
gene 1..1701
/gene="HA"
CDS 1..1701
/gene="HA"
/codon_start=1
/product="hemagglutinin"
/protein_id="AEJ83841.1"
/db_xref="GI:339518897"
/translation="MKAILVVLLYTFATANADTLCIGYHANNSTDTVDTVLEKNVTVT
HSVNLLEDKHNGKLCKLRGIAPLHLGKCNIAGWILGNPECESLSTASSWSYIVETSSS
DNGTCYPGDFINYEELREQLSSVSSFERFEIFPKTSSWPNHDSNKGVTAACPHVGAKS
FYKNLIWLVKKGNSYPKLSKSYINDKGKEVLVLWGIHHPSTTADQQSLYQNADAYVFV
GTSRYSKKFKPEIAIRPKVRXQEGRMNYYWTLVEPGDKITFEATGNLVVPRYAFAMER
NAGSGIIISDTPVHDCNTTCQTPKGAINTSLPFQNIHPITIGKCPKYVKSTKLRLATG
LRNVPSIQSRGLFGAIAGFIEGGWTGMVDGWYGYHHQNEQGSGYAADLKSTQNAIDKI
TNKVNSVIEKMNTQFTAVGKEFNHLEKRIENLNKKVDDGFLDIWTYNAELLVLLENER
TLDYHDSNVKNLYEKVRNQLKNNAKEIGNGCFEFYHKCDNTCMESVKNGTYDYPKYSE
EAKLNREEIDGVKLESTRIYQILAIYSTVASSLVLVVSLGAISFWMCSNGSLQCRICI
"
ORIGIN
1 atgaaggcaa tactagtagt tctgctatat acatttgcaa ccgcaaatgc agacacatta
61 tgtataggtt atcatgcgaa caattcaaca gacactgtag acacagtact agaaaagaat
121 gtaacagtaa cacactctgt taaccttcta gaagacaagc ataacgggaa actatgcaaa
181 ctaagaggga tagccccatt gcatttgggt aaatgtaaca ttgctggctg gatcctggga
241 aatccagagt gtgaatcact ctccacagca agctcatggt cctacattgt ggaaacatct
301 agttcagaca atggaacgtg ttacccagga gatttcatca attatgagga gctaagagag
361 caattgagct cagtgtcatc atttgaaagg tttgagatat tccccaagac aagttcatgg
421 cccaatcatg actcgaacaa aggtgtaacg gcagcatgtc ctcatgttgg agcaaaaagc
481 ttctacaaaa atttaatatg gctagttaaa aaaggaaatt catacccaaa gctcagcaaa
541 tcctacatta atgataaagg gaaagaagtc ctcgtgctat ggggcattca ccatccatct
601 actactgctg accaacaaag tctctatcag aatgcagatg catatgtttt tgtggggaca
661 tcaagataca gcaagaagtt caagccggaa atagcaataa gacccaaagt gaggrrtcaa
721 gaagggagaa tgaactatta ctggacacta gtagagccgg gagacaaaat aacattcgaa
781 gcaactggaa atctagtggt accgagatat gcattcgcaa tggaaagaaa tgctggatct
841 ggtattatca tttcagatac accagtccac gattgcaata caacttgtca gacacccaag
901 ggtgctataa acaccagcct cccatttcag aatatacatc cgatcacaat tggaaaatgt
961 ccaaaatatg taaaaagcac aaaattgaga ctggccacag gattgaggaa tgtcccgtct
1021 attcaatcta gaggcctatt tggggccatt gccggcttca ttgaaggggg gtggacaggg
1081 atggtagatg gatggtacgg ttatcaccat caaaatgagc aggggtcagg atatgcagcc
1141 gacctgaaga gcacacagaa tgccattgac aagattacta acaaagtaaa ttctgttatt
1201 gaaaagatga atacacagtt cacagcagta ggtaaagagt tcaaccacct ggaaaaaaga
1261 atagagaatt taaataaaaa agttgatgat ggtttcctgg acatttggac ttacaatgcc
1321 gaactgttgg ttctattgga aaatgaaaga actttggact accacgattc aaatgtgaag
1381 aacttatatg aaaaggtaag aaaccagtta aaaaacaatg ccaaggaaat tggaaacggc
1441 tgctttgaat tttaccacaa atgtgataac acgtgcatgg aaagtgtcaa aaatgggact
1501 tatgactacc caaaatactc agaggaagca aaattaaaca gagaagaaat agatggggta
1561 aagctggaat caacaaggat ttaccagatt ttggcgatct attcaactgt cgccagttca
1621 ttggtactgg tagtctccct gggggcaatc agtttctgga tgtgctccaa tgggtctcta
1681 cagtgtagaa tatgtattta a

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A/Tula/CRIE-SIA/2011 GACCCAAAGTGAGGGATCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Tula/CRIE-KiP/2011 GACCCAAAGTGAGGGATCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/St.Petersburg/CRIE-RME/2011 GACCCAAAGTGAGGRRTCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Tula/CRIE-ShEI/2011 GACCCAAAGTGAGGGATCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Tula/CRIE-LMV/2011 GACCCAAAGTGAGGGATCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Tula/CRIE-FeN/2011 GACCCAAAGTGAGGGATCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Tula/CRIE-MIM/2011 GACCCAAAGTGAGGGATCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Tver/CRIE-ZGNF/2011 GACCCAAAGTGAGGGGTCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Ufa/CRIE-XFM/2011 GACCCAAAGTGAGGGATCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Nizhnii_Novgorod/CRIE-SVN/20 GACCCAAAGTGAGGGGTCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Moscow_oblast/CRIE-SchNG/201 GACCCAAAGTGAGGAATCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Penza/CRIE-POC/2011 GACCCAAAGTGAGGAATCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Nizhnii_Novgorod/CRIE-AVA/20 GACCCAAAGTGAGGRRTCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Nizhnii_Novgorod/CRIE-LAN/20 GACCCAAAGTGAGGRRTCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Izhevsk/CRIE-AEM/2011 GACCCAAAGTGAGGRATCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Tula/CRIE-KEE/2011 GACCCAAAGTGAGGGATCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Nizhnii_Novgorod/CRIE-OAV/20 GACCCAAAGTGAGGGATCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Nizhnii_Novgorod/CRIE-LAV/20 GACCCAAAGTGAGGGGTCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Nizhnii_Novgorod/CRIE-UBA/20 GACCCAAAGTGAGGRRTCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Orenburg/CRIE-GLM/2011 GACCCAAAGTGAGGGGTCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Archangelsk/CRIE-SPA/2011 GACCCAAAGTGAGGGATCAAGAAGGGAGAATGAACTATTACTGGACACTA 750
A/Nizhnii_Novgorod/CRIE-BGF/20 GACCCAAAGTAAGGRRTCAAGAAGGGAGAATGAACTATTACTGGACACTA 750

_________________
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LOCUS JN185108 1701 bp cRNA linear VRL 01-SEP-2011
DEFINITION Influenza A virus (A/Nizhnii Novgorod/CRIE-BGF/2011(H1N1)) segment
4 hemagglutinin (HA) gene, complete cds.
ACCESSION JN185108
VERSION JN185108.1 GI:339518898
DBLINK Project: 37813
KEYWORDS .
SOURCE Influenza A virus (A/Nizhnii Novgorod/CRIE-BGF/2011(H1N1))
ORGANISM Influenza A virus (A/Nizhnii Novgorod/CRIE-BGF/2011(H1N1))
Viruses; ssRNA negative-strand viruses; Orthomyxoviridae;
Influenzavirus A.
REFERENCE 1 (bases 1 to 1701)
AUTHORS Yatsyshina,S., Minenko,A., Braslavskaya,S., Kudryavtseva,A. and
Shipulin,G.
TITLE Molecular characterisation of Influenza virus A/H1N1v in Russia in
2011
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1701)
AUTHORS Yatsyshina,S., Minenko,A., Braslavskaya,S., Kudryavtseva,A. and
Shipulin,G.
TITLE Direct Submission
JOURNAL Submitted (27-JUN-2011) Federal Budget Institute of Science,
Central Research Institute for Epidemiology, 3A, Novogireevskaya,
Moscow 111123, Russia
FEATURES Location/Qualifiers
source 1..1701
/organism="Influenza A virus (A/Nizhnii
Novgorod/CRIE-BGF/2011(H1N1))"
/mol_type="viral cRNA"
/strain="A/Nizhnii Novgorod/CRIE-BGF/2011"
/serotype="H1N1"
/isolation_source="autopsy lung tissue"
/host="Homo sapiens"
/db_xref="taxon:1050885"
/segment="4"
/country="Russia"
/collection_date="23-Jan-2011"
/note="lineage: swl"
gene 1..1701
/gene="HA"
CDS 1..1701
/gene="HA"
/codon_start=1
/product="hemagglutinin"
/protein_id="AEJ83842.1"
/db_xref="GI:339518899"
/translation="MKAILVVLLYTFATANADTLCIGYHANNSTDTVDTVLEKNVTVT
HSVNLLEDKHNGKLCKLRGVAPLHLGKCNIAGWILGNPECESLSTANSWSYIVETSSS
DNGTCYPGDFIDYEELREQLSSVSSFERFEIFPKTNSWPNHDSNKGVTAACPHAGAKS
FYKNLIWLVKKGNSYPKLSKSYINDKGKEVLVLWGIHHPSTSADQQSLYQNADAYVFV
GTSRYSKKFKPEIAIRPKVRXQEGRMNYYWTLVEPGDKITFEATGNLVVPRYAFAMER
NAGSGIIISDTPAHDCNTTCQTPKGAINTSLPFQNIHPITIGKCPKYVKSTKLRLATG
LRNVPSIQSRGLFGAIAGFIEGGWTGMVDGWYGYHHQNEQGSGYAADLKSTQNAIDKI
TNKVNSVIEKMNTQFTAVGKEFNHLEKRIENLNKKVDDGFLDIWTYNAELLVLLENER
TLDYHDSNVKNLYEKVRSQLKNNAKEIGNGCFEFYHKCNNTCMESVKNGTYDYPKYSE
EAKLNREEIDGVKLESTRIYQILAIYSTVASSLVLVVSLGAISFWMCSNGSLQCRICI
"
ORIGIN
1 atgaaggcaa tactagtagt tctgctatat acatttgcaa ctgcaaatgc agacacatta
61 tgtataggtt atcatgcgaa caattcaaca gacactgtag acacagtact agaaaagaat
121 gtaacagtaa cacactctgt taaccttcta gaagacaagc ataacgggaa actatgcaaa
181 ctaagagggg tagccccatt gcatttgggt aaatgtaaca ttgctggctg gatcctggga
241 aatccagagt gtgaatcact ctccacagca aactcatggt cctacattgt ggaaacatct
301 agttcagaca atggaacgtg ttacccagga gatttcatcg attatgagga gctaagagag
361 caattgagct cagtgtcatc attcgaaagg tttgagatat tccccaagac aaattcatgg
421 cccaatcatg actcgaacaa aggtgtaacg gcagcatgtc ctcatgctgg agcaaaaagc
481 ttctacaaaa atttaatatg gctagttaaa aaaggaaatt catacccaaa gctcagcaaa
541 tcctacatta atgataaagg gaaagaagtc ctcgtgctat ggggcattca ccatccatct
601 actagtgctg accaacaaag tctctatcag aatgcagatg catatgtttt tgtgggaaca
661 tcaagataca gcaagaagtt caagccggaa atagcaataa gacccaaagt aaggrrtcaa
721 gaagggagaa tgaactatta ctggacacta gtagagccgg gagacaaaat aacattcgaa
781 gcaactggaa atctagtggt accgagatat gcattcgcaa tggaaagaaa tgctggatcg
841 ggtattatca tttcagatac accagcccac gattgcaaca caacttgtca gacacccaag
901 ggtgctataa acaccagcct cccatttcag aatatacatc cgatcacaat aggaaaatgt
961 ccaaaatatg taaaaagcac caaattgaga ctggccacag gattgaggaa tgtcccgtct
1021 attcaatcta gaggcctatt tggggccatt gccggtttca ttgaaggggg gtggacaggg
1081 atggtagatg gatggtacgg ttaccaccat caaaatgagc aggggtcagg atatgcagcc
1141 gacctgaaga gcacacagaa tgccattgac aagattacta acaaagtaaa ttctgttatt
1201 gaaaagatga atacacagtt cacagcagta ggtaaagagt tcaaccacct ggaaaaaaga
1261 atagagaatt taaataaaaa agttgatgat ggtttcctgg acatttggac ttacaatgcc
1321 gaactgttgg ttctactgga aaatgaaaga actttggact accacgattc aaatgtgaag
1381 aacttatatg aaaaggtaag aagccagtta aaaaacaatg ccaaggaaat tggaaacggc
1441 tgctttgaat tttaccacaa atgcaataac acgtgcatgg aaagtgtcaa aaatgggact
1501 tatgactacc caaaatactc agaggaagca aaattaaaca gagaagaaat agatggggta
1561 aagctggaat caacaaggat ttaccagatt ttggcgatct attcaactgt cgccagttca
1621 ttggtactgg tagtctccct gggggcaatc agtttctgga tgtgctccaa tgggtctcta
1681 cagtgtagaa tatgtattta a

_________________
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Eight of the Russia samples were nasophayngeal swabs (all from Tula plus Achangelsk) which were removed from the list above. Thus, D225G, D225N, or both were in 12 of the 14 autopsy lung samples.

_________________
www.twitter.com/hniman