Rhiza Labs FluTracker Forum

NIID released 22 HA sequences (at GISAID) from recent collections (late 2010 / early 2011). 19 of the sequences had S188T and 1 had S186P, while another had S186P as a mixture with wild type (in addition to S188T).

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Newly released HA sequences with S188T

EPI305497 A/YAMAGUCHI/34/2010 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305495 A/HIROSHIMA/50/2010 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305494 A/HIROSHIMA/24/2011 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305491 A/HIROSHIMA/17/2011 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305485 A/KITAKYUSYU/1/2011 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305482 A/KITAKYUSYU/9/2010 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305479 A/YOKOHAMA/31/2011 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305476 A/YOKOHAMA/29/2011 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305466 A/HIROSHIMA-C/2/2011 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305464 A/YAMAGATA/175/2010 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305453 A/Laos/O072/2010 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305452 A/Laos/O066/2010 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305451 A/FUKUSHIMA/138/2010 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305449 A/KITAKYUSYU/3/2011 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305445 A/KANAGAWA/90/2010 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305439 A/TOCHIGI/105/2010 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305438 A/GUNMA/30/2010 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047
EPI305437 A/FUKUOKA-C/37/2010 (A/H1N1 swl) segment 4 (HA) 27.0 6.05047

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Additional late 2010 sequences with S188T in Japan and South Korea
EPI305365 A/Incheon/2434/2010 (A/H1N1 swl) segment 4 (HA) 27.0 6.04811
EPI305364 A/Gyeongnam/3110/2010 (A/H1N1 swl) segment 4 (HA) 27.0 6.04811
EPI305358 A/HIROSHIMA/1/2011 (A/H1N1 swl) segment 4 (HA) 27.0 6.04811
EPI305356 A/NIIGATA/1563/2010 (A/H1N1 swl) segment 4 (HA) 27.0 6.04811
EPI305352 A/KOBE/435/2010 (A/H1N1 swl) segment 4 (HA) 27.0 6.04811

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Additional RBD changes included S193R in A/Busan/2370/2010 and L194A in A/KANAGAWA/90/2010.

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G158E (LOW REACTOR) with S188T also in A/FUKUSHIMA/138/2010 and A/YAMAGUCHI/34/2010.

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