Rhiza Labs FluTracker Forum

From memory, the vax takes 6 months to make. Would have been available post southern hemisphere winter.

They meet twice a year. They are getting ready to select the targets for the 2011/2012 northern hemisphere.
They use a VERY insenstive assay, so they tend to stick with the old targets, no reality required.

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www.twitter.com/hniman

If a previous shot of the same stuff gives you "immunity", what's the point of producing more of the same? Those who want a vax have already had one, and those who don't won't have one.

That's something I haven't been able to grasp. Did read on PFI that the only reason people need a new vax is because the flu (and thus vax) is different enough each year. That's why choosing the same seed strain for the pH1N1 for this flu season made no sense tp (non-scientific) me. I read that what ever immunity a person might have from either catching the flu or being vaxed lasts, it's just that next year's flu is usually different enough so that previous immunity doesn't work.

And supposedly people over 60 or 65 have immunity (if they caught another kind of H1N1 decades ago) to this one circulating.

I am very confused about this issue.

Dr. Niman, if you have any further elucidation, I for one will appreciate it.

There are two reasons for getting a vaccination. One is the constant evolution of the virus, and the other is a "booster". When the same virus is used in consecutive years. the evolution aspect is out of play. However, a new vaccination can act as a booster. Remember, for those under 8 and getting vaccinated for the first time, a second shot is recommended. Similarly, protocols in Europe were initially for two shots and it was initially thought that two shots would be required in general (but a strong response in the US trials allowed for a single shot).

_________________
www.twitter.com/hniman

What do you think of the WHO decision to use "an A/California/7/2009 (H1N1)-like virus" - again?

I have never thought that California/7 was a good choice.

_________________
www.twitter.com/hniman

Bhutan/72 has S186P and A189T.

_________________
www.twitter.com/hniman

A189T pedigree

EPI297194 A/Sendai/TU620/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI297023 A/Yamagata/158/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI297022 A/Yamagata/143/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI295516 A/Bhutan/72/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI295510 A/Nigeria/1939/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI295405 A/Venezuela/29/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI295399 A/El Salvador/798/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI294306 A/PERTH/219/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI291704 A/Oklahoma/11/1990 (A/H1N1) segment 4 (HA) 27.0 5.92884
EPI291696 A/Nebraska/01/1992 (A/H1N1) segment 4 (HA) 27.0 5.92884
EPI291688 A/Minnesota/18/1995 (A/H1N1) segment 4 (HA) 27.0 5.92884
EPI291680 A/Indiana/05/1995 (A/H1N1) segment 4 (HA) 27.0 5.92884
EPI291672 A/Indiana/01/1994 (A/H1N1) segment 4 (HA) 27.0 5.92884
EPI289626 A/swine/IL/25399-3/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI288322 A/Boston/701/2009 (A/H1N1) segment 4 (HA) 27.0 5.92884
EPI288210 A/Boston/602/2009 (A/H1N1) segment 4 (HA) 27.0 5.92884
EPI288202 A/Boston/595/2009 (A/H1N1) segment 4 (HA) 27.0 5.92884
EPI286988 A/CapeTown/29/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI283772 A/Habana/10295/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI283254 A/Madrid/1376961/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI280320 A/Pennsylvania/07/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI278896 A/Texas/03/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI278878 A/Mexico/2880/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI278690 A/YAMAGATA/143/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI278681 A/FUKUSHIMA/105/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI277633 A/Ashgabat/WR0865N/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI277563 A/YAMAGATA/158/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI276644 A/Illinois/AF2222/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI276632 A/Germany/AF2210/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI276629 A/Germany/AF2207/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI276610 A/Florida/AF2188/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI276602 A/District of Columbia/AF2180/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI276514 A/ENG/94760209/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI276473 A/ENG/94700028/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI273903 A/Taiwan/27/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI273900 A/California/09/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI273891 A/Dnipropetrovsk/445/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI273838 A/Wisconsin/06/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI273829 A/Kentucky/06/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI273792 A/Wisconsin/03/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI273789 A/Wisconsin/04/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI273738 A/Minnesota/04/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI273674 A/Arizona/06/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI273662 A/Texas/03/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI273656 A/Hawaii/06/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI273626 A/Arizona/03/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI272726 A/Taiwan/26/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI272582 A/KUMAMOTO/20/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI272408 A/NARA/2/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI270846 A/San Diego/INS197/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI270647 A/California/VRDL3/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI270535 A/California/VRDL122/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI270527 A/California/VRDL121/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI267760 A/New York/6530/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI266992 A/Mexico City/025/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI258934 A/Wisconsin/629-D01572/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI258598 A/California/VRDL97/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI258526 A/California/VRDL14/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI258510 A/California/VRDL12/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI258494 A/California/VRDL102/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI258478 A/California/VRDL100/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI258100 A/Guangxi-Fangcheng/SWL189/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI258092 A/Guangxi-Yuzhou/SWL128/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI258088 A/Guangxi-Fangcheng/SWL194/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI258084 A/Guangxi-Fangcheng/SWL188/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI257996 A/Guangxi-Fangcheng/SWL183/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI257988 A/Guangxi-Fangcheng/SWL184/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI257856 A/Guangxi-Fangcheng/SWL179/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI257852 A/Guangxi-Fangcheng/SWL175/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI257568 A/Hubei-Wujiagang/SWL16/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI257564 A/Hubei-Wujiagang/SWL12/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI257472 A/Guangxi-Yuzhou/SWL11/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI257272 A/Guangdong-Haizhu/SWL1644/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI256414 A/Guangdong-Luohu/SWL1754/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI255861 A/Aswan/2288/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI255736 A/swine/Hong Kong/NS1892/2009 (A/H1N2) segment 4 (HA) 27.0 5.92884
EPI255728 A/swine/Hong Kong/NS1890/2009 (A/H1N2) segment 4 (HA) 27.0 5.92884
EPI255720 A/swine/Hong Kong/NS1889/2009 (A/H1N2) segment 4 (HA) 27.0 5.92884
EPI255331 A/swine/Hong Kong/NS1809/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI255010 A/New York/7020/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI254962 A/New York/6943/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI254438 A/Florida/13/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI252674 A/Texas/46222134/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI252530 A/Ontario/328474/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI249895 A/Nagasaki/HA-10-13/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI249694 A/Texas/46193311/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI249340 A/Wisconsin/629-D01846/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI249308 A/Wisconsin/629-D01556/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI249292 A/Wisconsin/629-D01244/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI249228 A/Wisconsin/629-D00459/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI248394 A/Wisconsin/629-S1313/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI248378 A/Wisconsin/629-S1252/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI248282 A/Wisconsin/629-D01987/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI248250 A/Wisconsin/629-D01826/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI248194 A/Wisconsin/629-D01473/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI248098 A/Wisconsin/629-D01140/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI248066 A/Wisconsin/629-D00968/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI247681 A/New York/5271/2009 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI247503 A/Wisconsin/02/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884
EPI247405 A/North Carolina/04/2010 (A/H1N1 swl) segment 4 (HA) 27.0 5.92884

_________________
www.twitter.com/hniman

There are two reasons for getting a vaccination. One is the constant evolution of the virus, and the other is a "booster". When the same virus is used in consecutive years. the evolution aspect is out of play. However, a new vaccination can act as a booster. Remember, for those under 8 and getting vaccinated for the first time, a second shot is recommended. Similarly, protocols in Europe were initially for two shots and it was initially thought that two shots would be required in general (but a strong response in the US trials allowed for a single shot).[/quote]

Thanks.

Re the booster, many folk here had the original mono swine flu shot, then later had the triple flu seasonal shot (including swine flu) = two shots.

Is there any point in getting a third shot "booster"?