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PostPosted: Sun May 09, 2010 7:47 am 
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A large series of low path H5 sequences from South Korea is being released. These are from aquatic birds and isolated from feces (so exact species is not known). These are predominantly H5N2 and H5N3 and although they are low path (for poultry), they have D225G and infected mice have virus in their lungs. These low path H5 sequences also recombine with high path H5 to increave the speed of H5 evolution.

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PostPosted: Sun May 09, 2010 7:49 am 
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niman wrote:
A large series of low path H5 sequences from South Korea is being released. These are from aquatic birds and isolated from feces (so exact species is not known). These are predominantly H5N2 and H5N3 and although they are low path (for poultry), they have D225G and infected mice have virus in their lungs. These low path H5 sequences also recombine with high path H5 to increave the speed of H5 evolution.

Here are some of the sequences being released

gb|GU361231.1| Influenza A virus (A/aquatic bird/Korea/w351/2... 40.1 0.051
gb|GU361230.1| Influenza A virus (A/aquatic bird/Korea/w347/2... 40.1 0.051
gb|GU361229.1| Influenza A virus (A/aquatic bird/Korea/w344/2... 40.1 0.051
gb|GU361228.1| Influenza A virus (A/aquatic bird/Korea/w209/2... 40.1 0.051
gb|GU361227.1| Influenza A virus (A/aquatic bird/Korea/w236/2... 40.1 0.051
gb|GU361226.1| Influenza A virus (A/aquatic bird/Korea/w235/2... 40.1 0.051
gb|GU361225.1| Influenza A virus (A/aquatic bird/Korea/w234/2... 40.1 0.051
gb|GU361224.1| Influenza A virus (A/aquatic bird/Korea/w231/2... 40.1 0.051
gb|GU361223.1| Influenza A virus (A/aquatic bird/Korea/w230/2... 40.1 0.051
gb|GU361222.1| Influenza A virus (A/aquatic bird/Korea/w229/2... 40.1 0.051
gb|GU361221.1| Influenza A virus (A/aquatic bird/Korea/w222/2... 40.1 0.051
gb|GU361220.1| Influenza A virus (A/aquatic bird/Korea/w221/2... 40.1 0.051
gb|GU361219.1| Influenza A virus (A/aquatic bird/Korea/w218/2... 40.1 0.051
gb|GU361218.1| Influenza A virus (A/aquatic bird/Korea/w217/2... 40.1 0.051
gb|GU361217.1| Influenza A virus (A/aquatic bird/Korea/w216/2... 40.1 0.051
gb|GU361216.1| Influenza A virus (A/aquatic bird/Korea/w211/2... 40.1 0.051
gb|GU361215.1| Influenza A virus (A/aquatic bird/Korea/w208/2... 40.1 0.051
gb|GU361213.1| Influenza A virus (A/aquatic bird/Korea/w205/2... 40.1 0.051
gb|GU361212.1| Influenza A virus (A/aquatic bird/Korea/w204/2... 40.1 0.051
gb|GU361211.1| Influenza A virus (A/aquatic bird/Korea/w202/2... 40.1 0.051
gb|GU361210.1| Influenza A virus (A/aquatic bird/Korea/w200/2... 40.1 0.051
gb|GU361209.1| Influenza A virus (A/aquatic bird/Korea/w198/2... 40.1 0.051
gb|GU361208.1| Influenza A virus (A/aquatic bird/Korea/w193/2... 40.1 0.051
gb|GU361207.1| Influenza A virus (A/aquatic bird/Korea/w191/2... 40.1 0.051
gb|GU361206.1| Influenza A virus (A/aquatic bird/Korea/w164/2... 40.1 0.051
gb|GU361205.1| Influenza A virus (A/aquatic bird/Korea/w163/2... 40.1 0.051
gb|GU361204.1| Influenza A virus (A/aquatic bird/Korea/w161/2... 40.1 0.051
gb|GU361203.1| Influenza A virus (A/aquatic bird/Korea/w132/2... 40.1 0.051
gb|GU361202.1| Influenza A virus (A/aquatic bird/Korea/w125/2... 40.1 0.051
gb|GU361201.1| Influenza A virus (A/aquatic bird/Korea/w121/2... 40.1 0.051
gb|GU361200.1| Influenza A virus (A/aquatic bird/Korea/w120/2... 40.1 0.051
gb|GU361199.1| Influenza A virus (A/aquatic bird/Korea/w114/2... 40.1 0.051
gb|GU361198.1| Influenza A virus (A/aquatic bird/Korea/w113/2... 40.1 0.051
gb|GU361197.1| Influenza A virus (A/aquatic bird/Korea/w96/20... 40.1 0.051
gb|GU361196.1| Influenza A virus (A/aquatic bird/Korea/w81/20... 40.1 0.051
gb|GU361195.1| Influenza A virus (A/aquatic bird/Korea/w79/20... 40.1 0.051
gb|GU361194.1| Influenza A virus (A/aquatic bird/Korea/w74/20... 40.1 0.051
gb|GU361193.1| Influenza A virus (A/aquatic bird/Korea/w54/20... 40.1 0.051
gb|GU361192.1| Influenza A virus (A/aquatic bird/Korea/w16/20... 40.1 0.051

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PostPosted: Sun May 09, 2010 9:49 am 
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A recent paper out of Eddie Holmes' lab tries again to claim that the examples of recombination are lab error

http://www.plosone.org/article/fetchObj ... tation=PDF

This group has been denying recombination for years, and the latest is more of the same. They are clearly circling the wagons, as more and more examples of recombination are published and they try to exclude portions of the sequence database that they don't control.

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PostPosted: Sun May 09, 2010 10:12 am 
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niman wrote:
A recent paper out of Eddie Holmes' lab tries again to claim that the examples of recombination are lab error

http://www.plosone.org/article/fetchObj ... tation=PDF

This group has been denying recombination for years, and the latest is more of the same. They are clearly circling the wagons, as more and more examples of recombination are published and they try to exclude portions of the sequence database that they don't control.

The above paper has a table with hundreds of examples of recombination, so the authors say if they were not done through the influenza sequencing project (which they control), the data isn't real.

Random mutation is in its final death throes, and the above paper is a good example of the increasing desperation.

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PostPosted: Sun May 09, 2010 11:49 am 
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niman wrote:
A recent paper out of Eddie Holmes' lab tries again to claim that the examples of recombination are lab error

http://www.plosone.org/article/fetchObj ... tation=PDF

This group has been denying recombination for years, and the latest is more of the same. They are clearly circling the wagons, as more and more examples of recombination are published and they try to exclude portions of the sequence database that they don't control.

I have started a separtate thread for discussing the above paper

viewtopic.php?f=5&t=5316

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PostPosted: Sun May 09, 2010 3:43 pm 
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Ok , Now I do get it, thanks.


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PostPosted: Sun May 09, 2010 3:58 pm 
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novascotia35 wrote:
Ok , Now I do get it, thanks.

Influenza genetic is all about politics. The "random mutation" enthusiasts are ander increasing pressure, and the latest Harbin data should lead to some rather curious responses, as these enthusiasts try to maintain their fanatsy and continue to jeapordize the world's health.

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PostPosted: Mon Aug 29, 2011 6:30 am 
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FAO now acknowledging clade 2.3.2 spread.

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