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 Post subject: Re: D225G In Japan
PostPosted: Fri Jan 29, 2010 10:23 am 
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Joined: Wed Aug 19, 2009 10:42 am
Posts: 6528
Location: Pittsburgh, PA USA
niman wrote:
C940T travel log

gb|CY054979.1| Influenza A virus (A/California/VRDL55/2009(H1... 32.2 12
gb|CY054939.1| Influenza A virus (A/California/VRDL48/2009(H1... 32.2 12
gb|CY054931.1| Influenza A virus (A/California/VRDL45/2009(H1... 32.2 12
gb|CY054899.1| Influenza A virus (A/California/VRDL39/2009(H1... 32.2 12
gb|CY054891.1| Influenza A virus (A/California/VRDL38/2009(H1... 32.2 12
gb|CY054851.1| Influenza A virus (A/California/VRDL32/2009(H1... 32.2 12
gb|CY054715.1| Influenza A virus (A/California/VRDL5/2009(H1N... 32.2 12
gb|GU369672.1| Influenza A virus (A/Ankara/28/2009(H1N1)) seg... 32.2 12
gb|CY052951.1| Influenza A virus (A/Texas/45061755/2009(H1N1)... 32.2 12
gb|CY052631.1| Influenza A virus (A/Texas/45061670/2009(H1N1)... 32.2 12
gb|CY052607.1| Influenza A virus (A/Texas/45034157/2009(H1N1)... 32.2 12
dbj|AB535745.1| Influenza A virus (A/Nagasaki/HA-53/2009(H1N1... 32.2 12
dbj|AB535744.1| Influenza A virus (A/Nagasaki/HA-52/2009(H1N1... 32.2 12
dbj|AB530488.1| Influenza A virus (A/Nagasaki/HA-44/2009(H1N1... 32.2 12
gb|GQ457514.1| Influenza A virus (A/California/25/2009(H1N1))... 32.2 12
gb|GQ422381.1| Influenza A virus (A/Milan/83/2009(H1N1)) segm... 32.2 12
gb|GQ387430.1| Influenza A virus (A/Catalonia/378/2009(H1N1))... 32.2 12
gb|GQ387382.1| Influenza A virus (A/Italy/172/2009(H1N1)) hem... 32.2 12
gb|GQ351314.1| Influenza A virus (A/Hong Kong/2369/2009(H1N1)... 32.2 12

Note that each of the above sequences, which like Yokahama/247 has C940T, has D225E, including the Hong Kong isolate with H274Y.

However, the Yokahama isolates has appended D716A onto the D225E background and converted D225E to D225G. This D225E background is distinct from the D225E in Europe, which also has examples of D225G on a D225E background.

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Last edited by niman on Fri Jan 29, 2010 10:30 am, edited 1 time in total.

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 Post subject: Re: D225G In Japan
PostPosted: Fri Jan 29, 2010 10:30 am 
Online

Joined: Wed Aug 19, 2009 10:42 am
Posts: 6528
Location: Pittsburgh, PA USA
niman wrote:
niman wrote:
C940T travel log

gb|CY054979.1| Influenza A virus (A/California/VRDL55/2009(H1... 32.2 12
gb|CY054939.1| Influenza A virus (A/California/VRDL48/2009(H1... 32.2 12
gb|CY054931.1| Influenza A virus (A/California/VRDL45/2009(H1... 32.2 12
gb|CY054899.1| Influenza A virus (A/California/VRDL39/2009(H1... 32.2 12
gb|CY054891.1| Influenza A virus (A/California/VRDL38/2009(H1... 32.2 12
gb|CY054851.1| Influenza A virus (A/California/VRDL32/2009(H1... 32.2 12
gb|CY054715.1| Influenza A virus (A/California/VRDL5/2009(H1N... 32.2 12
gb|GU369672.1| Influenza A virus (A/Ankara/28/2009(H1N1)) seg... 32.2 12
gb|CY052951.1| Influenza A virus (A/Texas/45061755/2009(H1N1)... 32.2 12
gb|CY052631.1| Influenza A virus (A/Texas/45061670/2009(H1N1)... 32.2 12
gb|CY052607.1| Influenza A virus (A/Texas/45034157/2009(H1N1)... 32.2 12
dbj|AB535745.1| Influenza A virus (A/Nagasaki/HA-53/2009(H1N1... 32.2 12
dbj|AB535744.1| Influenza A virus (A/Nagasaki/HA-52/2009(H1N1... 32.2 12
dbj|AB530488.1| Influenza A virus (A/Nagasaki/HA-44/2009(H1N1... 32.2 12
gb|GQ457514.1| Influenza A virus (A/California/25/2009(H1N1))... 32.2 12
gb|GQ422381.1| Influenza A virus (A/Milan/83/2009(H1N1)) segm... 32.2 12
gb|GQ387430.1| Influenza A virus (A/Catalonia/378/2009(H1N1))... 32.2 12
gb|GQ387382.1| Influenza A virus (A/Italy/172/2009(H1N1)) hem... 32.2 12
gb|GQ351314.1| Influenza A virus (A/Hong Kong/2369/2009(H1N1)... 32.2 12

Note that each of the above sequences, which like Yokahama/247 has C940T, has D225E, including the Hong Kong isolate with H274Y.

However, the Yokahama isolates has appended G716A onto the D225E background and converted D225E to D225G. This D225E background is distinct from the D225E in Europe, which also has examples of D225G on a D225E background.

TN17, which has H274Y and D225E, also has C940T.

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 Post subject: Re: D225G In Japan
PostPosted: Fri Jan 29, 2010 11:59 am 
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Joined: Wed Aug 19, 2009 10:42 am
Posts: 6528
Location: Pittsburgh, PA USA
A/Shiga/43/2009 also has C940T as well as D225E and H274Y. the clustering of H274Y in this sub-clade provides addition evidnece for the transmission of H274Y in the US and Japan.

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 Post subject: Re: D225G In Japan
PostPosted: Fri Jan 29, 2010 12:55 pm 
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Joined: Wed Aug 19, 2009 10:42 am
Posts: 6528
Location: Pittsburgh, PA USA
Commentary

http://www.recombinomics.com/News/01291 ... Japan.html

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