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 Post subject: Samples From Turkey with D225E
PostPosted: Mon Jan 04, 2010 6:33 pm 
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29 HA sequences from Turkey deposited today on NCBI database. 3 are partial.

I am just learning how to interpret these sequences, but it appears to me that 9 samples have D225E and one D225N.

Niman, can you please review and confirm?


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 Post subject: Re: Samples From Turkey with D225E
PostPosted: Mon Jan 04, 2010 6:39 pm 
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Location: Pittsburgh, PA USA
spentitall wrote:
29 HA sequences from Turkey deposited today on NCBI database. 3 are partial.

I am just learning how to interpret these sequences, but it appears to me that 9 samples have D225E and one D225N.

Niman, can you please review and confirm?

I am just starting to look. I believe several also have N231D.

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 Post subject: Re: Samples From Turkey with D225E
PostPosted: Mon Jan 04, 2010 7:07 pm 
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Location: Pittsburgh, PA USA
spentitall wrote:
29 HA sequences from Turkey deposited today on NCBI database. 3 are partial.

I am just learning how to interpret these sequences, but it appears to me that 9 samples have D225E and one D225N.

Niman, can you please review and confirm?

My quick count was 8 with D225E and 1 D225N (and 2 with N231D). Many were partials and three may not include the RBD.

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 Post subject: Re: Samples From Turkey with D225E
PostPosted: Mon Jan 04, 2010 7:17 pm 
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Thanks.


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 Post subject: Re: Samples From Turkey with D225E
PostPosted: Mon Jan 04, 2010 7:57 pm 
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Niman,

Not that it matters, but once I realized I counted the D225N twice, I come up with the same numbers.

Do you have a search function on your Recombinomics site? Several times I have wanted to search your commentaries. Maybe it's there and I can't find it. I know you've mentioned N231 before and would like to avoid having to ask you to re-iterate everything for those of challenged with short memories.


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 Post subject: Re: Samples From Turkey with D225E
PostPosted: Mon Jan 04, 2010 10:52 pm 
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I guess we won't be hearing any updates on deaths from Turkey. Unless it get's really bad, or becomes insignificant.

http://english.sol.org.tr/news/turkey/s ... lared-1012

"Swine flu deaths won’t be declared”
Thursday, 24 December 2009

Ministry of Health stated that the number of deaths from swine flu won’t be declared unless there is an extreme increase or decrease.

The Ministry of Health announced with a written statement that “the number of the ones who lost their live because of swine flu” won’t be declared unless there is an extreme increase or decrease. The Ministry also said that the number of people who are immune to the swine flu is 6 million with the ones who got vaccination.

According to the statement, the disease is seen in all cities of Turkey and caused death in 67 of them. One third of the people who lost their lives were under 50 and healthy, 181 people were in intensive care.

The Ministry did not give information about the number of deaths recently.

(soL - News Desk)"


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 Post subject: Re: Samples From Turkey with D225E
PostPosted: Tue Jan 05, 2010 10:48 am 
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Location: Pittsburgh, PA USA
spentitall wrote:
Niman,

Not that it matters, but once I realized I counted the D225N twice, I come up with the same numbers.

Do you have a search function on your Recombinomics site? Several times I have wanted to search your commentaries. Maybe it's there and I can't find it. I know you've mentioned N231 before and would like to avoid having to ask you to re-iterate everything for those of challenged with short memories.

Commentraies are searchable by google within a few minutes of posting, so a google search that includes the term recombinomics, will pull up commentaries with appropriate hits (the time can alos be filtered in google searches).

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 Post subject: Re: Samples From Turkey with D225E
PostPosted: Tue Jan 05, 2010 10:49 am 
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Joined: Wed Aug 19, 2009 10:42 am
Posts: 6528
Location: Pittsburgh, PA USA
spentitall wrote:
Niman,

Not that it matters, but once I realized I counted the D225N twice, I come up with the same numbers.

Do you have a search function on your Recombinomics site? Several times I have wanted to search your commentaries. Maybe it's there and I can't find it. I know you've mentioned N231 before and would like to avoid having to ask you to re-iterate everything for those of challenged with short memories.

Updated D225E list

gb|GU369672.1| Influenza A virus (A/Ankara/28/2009(H1N1)) seg... 30.2 47
gb|GU369662.1| Influenza A virus (A/Ankara/18/2009(H1N1)) seg... 30.2 47
gb|GU369660.1| Influenza A virus (A/Ankara/16/2009(H1N1)) seg... 30.2 47
gb|GU369659.1| Influenza A virus (A/Ankara/15/2009(H1N1)) seg... 30.2 47
gb|GU369658.1| Influenza A virus (A/Ankara/14/2009(H1N1)) seg... 30.2 47
gb|GU369656.1| Influenza A virus (A/Ankara/12/2009(H1N1)) seg... 30.2 47
gb|GU369652.1| Influenza A virus (A/Ankara/08/2009(H1N1)) seg... 30.2 47
gb|GU369648.1| Influenza A virus (A/Ankara/05/2009(H1N1)) seg... 30.2 47
gb|CY053401.1| Influenza A virus (A/Catalonia/S2010/2009(H1N1... 30.2 47
gb|CY053391.1| Influenza A virus (A/Catalonia/S1947/2009(H1N1... 30.2 47
gb|CY053385.1| Influenza A virus (A/Catalonia/S1944/2009(H1N1... 30.2 47
gb|CY052951.1| Influenza A virus (A/Texas/45061755/2009(H1N1)... 30.2 47
gb|CY052631.1| Influenza A virus (A/Texas/45061670/2009(H1N1)... 30.2 47
gb|CY052607.1| Influenza A virus (A/Texas/45034157/2009(H1N1)... 30.2 47
dbj|AB535744.1| Influenza A virus (A/Nagasaki/HA-52/2009(H1N1... 30.2 47
gb|CY052042.1| Influenza A virus (A/Catalonia/S1835/2009(H1N1... 30.2 47
gb|CY052040.1| Influenza A virus (A/Catalonia/S1834/2009(H1N1... 30.2 47
gb|CY052036.1| Influenza A virus (A/Catalonia/S1830/2009(H1N1... 30.2 47
gb|CY052034.1| Influenza A virus (A/Catalonia/S1829/2009(H1N1... 30.2 47
gb|CY052032.1| Influenza A virus (A/Catalonia/S1828/2009(H1N1... 30.2 47
gb|CY052019.1| Influenza A virus (A/Norway/3206-3/2009(H1N1))... 30.2 47
gb|CY052015.1| Influenza A virus (A/Norway/4023/2009(H1N1)) s... 30.2 47
gb|CY052007.1| Influenza A virus (A/Norway/3478/2009(H1N1)) s... 30.2 47
gb|CY051991.1| Influenza A virus (A/Norway/3059/2009(H1N1)) s... 30.2 47
gb|CY051987.1| Influenza A virus (A/Norway/2690/2009(H1N1)) s... 30.2 47
gb|CY051986.1| Influenza A virus (A/Norway/2674/2009(H1N1)) s... 30.2 47
gb|CY051982.1| Influenza A virus (A/Catalonia/S1761/2009(H1N1... 30.2 47
gb|CY051976.1| Influenza A virus (A/Catalonia/S1758/2009(H1N1... 30.2 47
gb|CY051964.1| Influenza A virus (A/Catalonia/S1748/2009(H1N1... 30.2 47
gb|CY051955.1| Influenza A virus (A/Catalonia/S1698/2009(H1N1... 30.2 47
gb|CY051940.1| Influenza A virus (A/Catalonia/S1674/2009(H1N1... 30.2 47
gb|CY051937.1| Influenza A virus (A/Catalonia/S1672/2009(H1N1... 30.2 47
gb|GU214058.1| Influenza A virus (A/Serbia/3547/2009(H1N1)) s... 30.2 47
gb|CY050319.1| Influenza A virus (A/Catalonia/S1641/2009(H1N1... 30.2 47
gb|CY050316.1| Influenza A virus (A/Catalonia/S1637/2009(H1N1... 30.2 47
gb|CY050313.1| Influenza A virus (A/Catalonia/S1632/2009(H1N1... 30.2 47
gb|CY050307.1| Influenza A virus (A/Catalonia/S1606/2009(H1N1... 30.2 47
gb|CY050304.1| Influenza A virus (A/Catalonia/S1605/2009(H1N1... 30.2 47
gb|CY050301.1| Influenza A virus (A/Catalonia/S1604/2009(H1N1... 30.2 47
dbj|AB530488.1| Influenza A virus (A/Nagasaki/HA-44/2009(H1N1... 30.2 47
gb|CY049742.1| Influenza A virus (A/Catalonia/S1592/2009(H1N1... 30.2 47
gb|CY049736.1| Influenza A virus (A/Catalonia/S1587/2009(H1N1... 30.2 47
gb|CY049728.1| Influenza A virus (A/Catalonia/S1545/2009(H1N1... 30.2 47
gb|CY049707.1| Influenza A virus (A/Catalonia/S1479/2009(H1N1... 30.2 47
gb|CY049704.1| Influenza A virus (A/Catalonia/S1478/2009(H1N1... 30.2 47
gb|CY049051.1| Influenza A virus (A/Catalonia/S1436/2009(H1N1... 30.2 47
gb|CY049027.1| Influenza A virus (A/Catalonia/S1379/2009(H1N1... 30.2 47
gb|CY049024.1| Influenza A virus (A/Catalonia/S1369/2009(H1N1... 30.2 47
gb|CY049018.1| Influenza A virus (A/Catalonia/S1350/2009(H1N1... 30.2 47
gb|CY049015.1| Influenza A virus (A/Catalonia/S1333/2009(H1N1... 30.2 47
gb|CY049012.1| Influenza A virus (A/Catalonia/S1331/2009(H1N1... 30.2 47
gb|CY049003.1| Influenza A virus (A/Catalonia/S1304/2009(H1N1... 30.2 47
gb|CY049000.1| Influenza A virus (A/Catalonia/S1300/2009(H1N1... 30.2 47
gb|CY047307.1| Influenza A virus (A/Catalonia/S1286/2009(H1N1... 30.2 47
gb|CY047290.1| Influenza A virus (A/Catalonia/S1273/2009(H1N1... 30.2 47
gb|CY047287.1| Influenza A virus (A/Catalonia/S1272/2009(H1N1... 30.2 47
gb|CY047278.1| Influenza A virus (A/Catalonia/S1269/2009(H1N1... 30.2 47
gb|CY047269.1| Influenza A virus (A/Catalonia/S1265/2009(H1N1... 30.2 47
gb|CY047266.1| Influenza A virus (A/Catalonia/S1260/2009(H1N1... 30.2 47
gb|CY047263.1| Influenza A virus (A/Catalonia/S1254/2009(H1N1... 30.2 47
gb|CY047257.1| Influenza A virus (A/Catalonia/S1249/2009(H1N1... 30.2 47
gb|CY047254.1| Influenza A virus (A/Catalonia/S1248/2009(H1N1... 30.2 47
gb|CY047243.1| Influenza A virus (A/Catalonia/S1237/2009(H1N1... 30.2 47
gb|CY047240.1| Influenza A virus (A/Catalonia/S1236/2009(H1N1... 30.2 47
gb|CY047230.1| Influenza A virus (A/Catalonia/S1227/2009(H1N1... 30.2 47
gb|CY047227.1| Influenza A virus (A/Catalonia/S1222/2009(H1N1... 30.2 47
gb|CY047221.1| Influenza A virus (A/Catalonia/S1215/2009(H1N1... 30.2 47
gb|CY047215.1| Influenza A virus (A/Catalonia/S1209/2009(H1N1... 30.2 47
gb|CY047203.1| Influenza A virus (A/Catalonia/S1205/2009(H1N1... 30.2 47
gb|CY047200.1| Influenza A virus (A/Catalonia/S1199/2009(H1N1... 30.2 47
gb|CY047188.1| Influenza A virus (A/Catalonia/S1187/2009(H1N1... 30.2 47
gb|CY047185.1| Influenza A virus (A/Catalonia/S1183/2009(H1N1... 30.2 47
gb|CY047182.1| Influenza A virus (A/Catalonia/S1182/2009(H1N1... 30.2 47
gb|CY047164.1| Influenza A virus (A/Catalonia/S1165/2009(H1N1... 30.2 47
gb|CY047158.1| Influenza A virus (A/Catalonia/S1161/2009(H1N1... 30.2 47
gb|CY047137.1| Influenza A virus (A/Catalonia/S1120/2009(H1N1... 30.2 47
gb|CY047083.1| Influenza A virus (A/Catalonia/NS2008/2009(H1N... 30.2 47
gb|CY047080.1| Influenza A virus (A/Catalonia/NS2001/2009(H1N... 30.2 47
gb|GQ485661.1| Influenza A virus (A/Almati/01/2009(H1N1)) seg... 30.2 47
gb|GQ457519.1| Influenza A virus (A/Changsha/78/2009(H1N1)) s... 30.2 47
gb|GQ457514.1| Influenza A virus (A/California/25/2009(H1N1))... 30.2 47
gb|GQ422381.1| Influenza A virus (A/Milan/83/2009(H1N1)) segm... 30.2 47
gb|GQ422380.1| Influenza A virus (A/Milan/80/2009(H1N1)) segm... 30.2 47
gb|GQ421203.1| Influenza A virus (A/Ancona/05/2009(H1N1)) seg... 30.2 47
gb|GQ387430.1| Influenza A virus (A/Catalonia/378/2009(H1N1))... 30.2 47
gb|GQ387382.1| Influenza A virus (A/Italy/172/2009(H1N1)) hem... 30.2 47
gb|GQ365446.1| Influenza A virus (A/Sapporo/1/2009(H1N1)) seg... 30.2 47
gb|GQ355305.1| Influenza A virus (A/Catalonia/387/2009(H1N1))... 30.2 47
gb|GQ351314.1| Influenza A virus (A/Hong Kong/2369/2009(H1N1)... 30.2 47

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 Post subject: Re: Samples From Turkey with D225E
PostPosted: Tue Jan 05, 2010 11:25 am 
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Joined: Wed Aug 19, 2009 10:42 am
Posts: 6528
Location: Pittsburgh, PA USA
This travel log suggests that Ankara 28 is Tamiflu resistant

gb|GU369672.1| Influenza A virus (A/Ankara/28/2009(H1N1)) seg... 38.2 0.19
gb|CY052951.1| Influenza A virus (A/Texas/45061755/2009(H1N1)... 38.2 0.19
gb|CY052631.1| Influenza A virus (A/Texas/45061670/2009(H1N1)... 38.2 0.19
gb|CY052607.1| Influenza A virus (A/Texas/45034157/2009(H1N1)... 38.2 0.19
dbj|AB535745.1| Influenza A virus (A/Nagasaki/HA-53/2009(H1N1... 38.2 0.19
dbj|AB535744.1| Influenza A virus (A/Nagasaki/HA-52/2009(H1N1... 38.2 0.19
dbj|AB530488.1| Influenza A virus (A/Nagasaki/HA-44/2009(H1N1... 38.2 0.19
gb|GQ457514.1| Influenza A virus (A/California/25/2009(H1N1))... 38.2 0.19
gb|GQ422381.1| Influenza A virus (A/Milan/83/2009(H1N1)) segm... 38.2 0.19
gb|GQ387430.1| Influenza A virus (A/Catalonia/378/2009(H1N1))... 38.2 0.19
gb|GQ387382.1| Influenza A virus (A/Italy/172/2009(H1N1)) hem... 38.2 0.19
gb|GQ351314.1| Influenza A virus (A/Hong Kong/2369/2009(H1N1)... 38.2 0.19

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 Post subject: Re: Samples From Turkey with D225E
PostPosted: Tue Jan 05, 2010 11:35 am 
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Joined: Wed Nov 04, 2009 2:14 am
Posts: 337
niman wrote:
Commentraies are searchable by google within a few minutes of posting, so a google search that includes the term recombinomics, will pull up commentaries with appropriate hits (the time can alos be filtered in google searches).


Well even if I learn nothing more about the flu from this forum, I've definitely increased my computer skills. I never realized that google searches the complete contents of a site, now I feel inept.

If Google search is right, I guess you haven't mentioned N231 in your commentaries. This forum was unusually quite last night! I was hoping for a new commentary this morning ;) , explaining the Turkish samples, more analysis and the possible significance of N231D along with D225E, or even multiple RBD changes.

No pressure, I know your busy.


Last edited by spentitall on Tue Jan 05, 2010 11:39 am, edited 1 time in total.

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