Rhiza Labs FluTracker Forum

Please. The D225G jumps just like H274Y. The threat is more real than ever, and the latest from Sweden has the same two adjacent changes, but on a different background.

The "experts" at ECDC are the same ones who were "shocked", "baffled", and "surprised" by H274Y jumping and becoming fixed on seasonal flu and they will be "shocked", "baffled", and "suprised" when H274Y follows the same pattern on pandemic H1N1 flu and the same thing happens at position 225.

The "experts' are as lost as ever because they are still defending the nonsense of "random mutations'

The "analysis" at flutrackers.com is nonsense posted by anonymous posters with no background in virology, genetics, or sequence analysis, which is all too common on these boards.

One who did analysis thought the one letter codes were "typos" and mixed infections were rare (and those without backgrounds actually believe that nonsense also).

These tandem changes are on a Swedish genetic background, which is distinct from the Utah sequence (on a Utah background) or Mexican sequences. This, the tandem changes jump together from background to background, once again supporting recombination, which remains the name of the game.

and , do we see other polymorphisms "jumping" around like this ?
If not, why ?
Seems to support the idea of independent development rather
than disproving it.

What I find intensely perplexing is that part of the human condition that lacks reflection and never acknowledges accurate contrary prediction, especially when it is highly polarized from the norm. WHO could have accurately assessed H274Y becoming fixed? -- CDC is finding it in just under 2% of cases in its last update and is global -- Japan, Vietnam, etc. I am not counting on any admission of their analyses being inherently flawed but am interested in how they present this info that is now "fixing".

If the D225G that makes the virus so much deadlier, is spreading effectively, and vaccine doesn't protect against it how come the deaths in countries like Sweden, Norway, Finland and Ukraine are not accelerating faster? Sweden for an example is only reporting 22 deaths, so are they hiding information or marking deaths caused by virus with D225G as caused by something else?

You have been given hundreds of examples. It is how influenza evolves. You call them lab errors or something usual.

Many examples are described here

http://precedings.nature.com/documents/2832/version/1

including doubles and triples.

You are always asking for examples, and when given the examples you ignore them and then ask the same question again (which you have been doing for YEARS).

D225G and D225N are emerging. The biggest moves will been when the current wild type fades away, as is happening now. Last spring there were no examples of D225G and D225N in the same person. Now there are four and all four sequences were released this month.

Time for a calendar check.

Commentary

http://www.recombinomics.com/News/12280 ... weden.html

Is 222G pretty-much synonymous with 225G? There is no mention of D225G in that article. They only refer to the 222 variants. Can their conclusions be so easily grandfathered over to the 225 variant?