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PostPosted: Thu Nov 20, 2014 4:50 pm 
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Commentary

http://www.recombinomics.com/News/11201 ... urope.html

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PostPosted: Fri Nov 28, 2014 2:44 pm 
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Location: Pittsburgh, PA USA
Highly pathogenic avian influenza,
United Kingdom

Information received on 27/11/2014 from Dr Nigel Gibbens, Chief Veterinary Officer, Department for Environment, Food and Rural Affairs, Department for Environment, Food and Rural Affairs, LONDON, United Kingdom
Summary
Report type Follow-up report No. 2
Date of start of the event 14/11/2014
Date of pre-confirmation of the event 16/11/2014
Report date 27/11/2014
Date submitted to OIE 27/11/2014
Reason for notification Reoccurrence of a listed disease
Date of previous occurrence 20/08/2008
Manifestation of disease Clinical disease
Causal agent Highly pathogenic avian influenza virus
Serotype H5N8
Nature of diagnosis Laboratory (advanced)
This event pertains to a defined zone within the country
Related reports Immediate notification (17/11/2014)
Follow-up report No. 1 (21/11/2014)
Follow-up report No. 2 (27/11/2014)
Outbreaks There are no new outbreaks in this report
Epidemiology
Source of the outbreak(s) or origin of infection
Unknown or inconclusive
Epidemiological comments Update on 27 November 2014 - The IVPI result is now available - 2.88 (highly pathogenic) - No further cases have been identified and surveillance and tracing activities have indicated no evidence of spread to date (27 November 2014) - The epidemiological investigation is ongoing and disease control measures remain in place. Updates will be provided in the weekly reports as further information becomes available.
Control measures
Measures applied
Stamping out
Quarantine
Movement control inside the country
Screening
Zoning
Disinfection of infected premises/establishment(s)
Vaccination prohibited
No treatment of affected animals
Measures to be applied
No other measures
Diagnostic test results
Laboratory name and type Species Test Test date Result
Animal and Plant Health Agency (APHA) Weybridge (OIE’s Reference Laboratory) Birds haemagglutination inhibition test (HIT) 16/11/2014 Negative
Animal and Plant Health Agency (APHA) Weybridge (OIE’s Reference Laboratory) Birds intravenous pathogenicity index (IVPI) test 21/11/2014 Positive
Animal and Plant Health Agency (APHA) Weybridge (OIE’s Reference Laboratory) Birds nucleotide sequencing 16/11/2014 Positive
Animal and Plant Health Agency (APHA) Weybridge (OIE’s Reference Laboratory) Birds reverse transcription - polymerase chain reaction (RT-PCR) 16/11/2014 Positive
Future Reporting
The event is continuing. Weekly follow-up reports will be submitted.

http://www.oie.int/wahis_2/public/wahid ... rtid=16626

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PostPosted: Tue Dec 23, 2014 11:28 am 
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Posts: 56044
Location: Pittsburgh, PA USA
nformation received on 22/12/2014 from Dr Nigel Gibbens, Chief Veterinary Officer, Department for Environment, Food and Rural Affairs, Department for Environment, Food and Rural Affairs, LONDON, United Kingdom
Summary
Report type Follow-up report No. 6
Date of start of the event 14/11/2014
Date of pre-confirmation of the event 16/11/2014
Report date 22/12/2014
Date submitted to OIE 22/12/2014
Reason for notification Reoccurrence of a listed disease
Date of previous occurrence 20/08/2008
Manifestation of disease Clinical disease
Causal agent Highly pathogenic avian influenza virus
Serotype H5N8
Nature of diagnosis Laboratory (advanced)
This event pertains to a defined zone within the country
Related reports Immediate notification (17/11/2014)
Follow-up report No. 1 (21/11/2014)
Follow-up report No. 2 (27/11/2014)
Follow-up report No. 3 (05/12/2014)
Follow-up report No. 4 (12/12/2014)
Follow-up report No. 5 (19/12/2014)
Follow-up report No. 6 (22/12/2014)
Outbreaks There are no new outbreaks in this report
Epidemiology
Source of the outbreak(s) or origin of infection
Unknown or inconclusive
Epidemiological comments No further cases have been identified to 22 December 2014. The 10 km surveillance zone was lifted on 21 December 2014 following the completion of the surveillance programme. A further update will now be provided in the next weekly report (w/c 29/12/14).
Control measures
Measures applied
Stamping out
Quarantine
Movement control inside the country
Screening
Zoning
Disinfection of infected premises/establishment(s)
Vaccination prohibited
No treatment of affected animals
Measures to be applied
No other measures
Diagnostic test results
Laboratory name and type Species Test Test date Result
Animal and Plant Health Agency (APHA), Weybridge (OIE’s Reference Laboratory) Birds intravenous pathogenicity index (IVPI) test 21/12/2014 Positive
Future Reporting
The event is continuing. Weekly follow-up reports will be submitted.

http://www.oie.int/wahis_2/public/wahid ... rtid=16808

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PostPosted: Wed Dec 24, 2014 5:26 am 
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Joined: Wed Aug 19, 2009 10:42 am
Posts: 56044
Location: Pittsburgh, PA USA
Department for Environment, Food and Rural Affairs
Animal Health & Veterinary Laboratories Agency
Veterinary & Science Policy Advice Team - International Disease Monitoring
1
Preliminary Outbreak Assessment
Highly Pathogenic Avian Influenza H5N8 in turkeys in
Germany
06 November 2014 Ref: VITT/1200 H5N8 HPAI in Germany
Disease Report
Germany has reported an outbreak of highly pathogenic avian influenza, H5N8 in fattening
turkeys in North East Germany (Mecklenburg Western Pomerania) (see map; OIE, 2014).
Increased mortality was observed in one of the six sheds of 15 week old birds for fattening
(total number of turkeys on the premises ~ 31,000 of which each shed contained 5,000).
Disease control measures
have been implemented
including 3km and 10km
protection and surveillance
zones in line with Directive
2005/94/EC and the birds in
the affected shed as well as
all other poultry in the
protection zone have been
destroyed. There have been
no recent traded
consignments from the
affected areas to the UK or
other Member States.
Situation Assessment
During the past year, HPAI H5N8 has been reported from several countries in the Far
East, in Japan, the Republic of Korea (ROK) and China (near the border with the
Democratic Republic of Korea). In ROK, in excess of thirty five outbreaks have been
reported since early 2014 from commercial poultry (principally breeding ducks but also
chickens) and additional detections in wild waterfowl, resulting in the destruction of over 12
million poultry. In China, positive samples were found at a market during routine
surveillance under the national plan. Japan reported just a single outbreak. Department for Environment, Food and Rural Affairs
Animal Health & Veterinary Laboratories Agency
Veterinary & Science Policy Advice Team - International Disease Monitoring
2
Genetic characterisation of the viruses from both poultry and wild birds in ROK and China
revealed there was very high sequence similarity with the haemagglutinin (HA) gene of
H5N1 HPAI viruses isolated
in China in 2011 and
clustered within clade 2.3.4.6
indicating this newly emerged
virus has derived following
reassortment of H5N1 HPAI
with other influenza viruses
co-circulating in avian
populations (Ku et al 2014;
Lee et al 2014; Wu et al
2014). The predicted putative
binding to host cell receptors
is similar to H5N1 HPAI,
preferentially binding the
‘avian’ receptor. However
although no human infections with this virus have been reported to date, the potential risk
to public health cannot be ignored.
Wild Waterfowl and commercial ducks have been found to harbour the virus in ROK (Lee
et al, 2014), where the infection caused depression, egg drop, some neurological signs
and a slight increase in mortality. There is currently no evidence for the virus being present
in wild waterfowl in Europe, although this possibility cannot be ruled out. In the absence of
any other epidemiological explanation, virus introduction into Germany via wild birds
appears highly plausible.
Conclusion
This is the season for increased wild bird migration especially waterfowl as well as
seasonal poultry production and therefore there is an increased risk of incursion of any
notifiable avian disease into the poultry sector through direct and indirect contact with wild
birds and / or poor biosecurity. The report in North East Germany at this time of year
therefore does increase the level of risk of incursion to the UK, although it is difficult to
predict quantitatively with any precise confidence without data on any potential reservoir
species and current wild bird demographics. However current UK wild bird surveillance
targeting higher risk species for H5N1 HPAI infection is aligned with current knowledge
from the Far East on carrier populations for H5N8.
We will continue to report on the situation. We would like to remind all poultry keepers to
maintain high standards of biosecurity, remain vigilant and report any suspect clinical signs
promptly.Department for Environment, Food and Rural Affairs
Animal Health & Veterinary Laboratories Agency
Veterinary & Science Policy Advice Team - International Disease Monitoring
3
Authors
Jonathan Smith
Professor Ian Brown
Dr Helen Roberts
References
Ku KB, Park EH, Yum J, Kim JA, Oh SK, Seo SH. Highly pathogenic avian influenza
A(H5N8) virus from waterfowl, South Korea, 2014 [letter]. Emerg Infect Dis [Internet].
2014 Sep [06/11/2014]. http://dx.doi.org/10.3201/eid2009.140390
Lee YJ, Kang HM, Lee EK, Song BM, Jeong J, Kwon YK, et al. Novel reassortant
influenza A(H5N8) viruses, South Korea, 2014 [letter]. Emerg Infect Dis [Internet]. 2014
Jun [06/11/2014]. http://dx.doi.org/10.3201/eid2006.140233
OIE (2014) Highly Pathogenic Avian Influenza virus. Immediate Notification report Report
Ref 14-015-00003; Ref OIE 16474 Report Date 06/11/2014.
http://www.oie.int/wahis_2/temp/reports ... 172613.pdf
Wu H, Peng X, Xu L, Jin C, Cheng L, Lu X, Novel Reassortant Influenza A(H5N8) Viruses
in Domestic Ducks, Eastern China. Emerg Infect Dis. 2014;20:1315–8.

https://www.gov.uk/government/uploads/s ... 141106.pdf

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