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100% of New H3N2 Cases In US In Week 45 Are Low Reactors
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Author:  niman [ Fri Nov 14, 2014 1:34 pm ]
Post subject:  100% of New H3N2 Cases In US In Week 45 Are Low Reactors

CDC has released data for week 45 antigen characterization for H3N2 (which represent almost all influenza A, the dominant type). Three new sequences were analyzed and all three were low reactors, increasing the frequency for the year to 46% (6/13), up from the initial data of 30% (3/10).

http://www.cdc.gov/flu/weekly/

Author:  niman [ Fri Nov 14, 2014 1:37 pm ]
Post subject:  Re: 100% of New H3N2 Cases In US In Week 45 Are Low Reactors

Influenza A (H3N2) [13]:

Seven (54%) of the 13 influenza A (H3N2) viruses tested have been characterized as A/Texas/50/2012-like, the influenza A (H3N2) component of the 2014-2015 Northern Hemisphere influenza vaccine. Six (46%) of the 13 viruses tested showed reduced titers with antiserum produced against A/Texas/50/2012. Among viruses that showed reduced titers with antiserum raised against A/Texas/50/2012, the majority were antigenically similar to A/Switzerland/9715293/2013, the H3N2 virus selected for the 2015 Southern Hemisphere influenza vaccine. A/Switzerland/9715293/2013 is related to, but antigenically and genetically distinguishable, from the A/Texas/50/2012 vaccine virus. A/Switzerland-like H3N2 viruses were first detected in the United States in small numbers in March of 2014 and began to circulate in greater numbers over the spring and summer.

Author:  niman [ Fri Nov 14, 2014 1:40 pm ]
Post subject:  Re: 100% of New H3N2 Cases In US In Week 45 Are Low Reactors

Dominance of H3N2 (99% of non-subtyped influenza A samples are H3N2)

Image

Author:  niman [ Fri Nov 14, 2014 1:48 pm ]
Post subject:  Re: 100% of New H3N2 Cases In US In Week 45 Are Low Reactors

Week 45
No. of specimens tested 9,138
No. of positive specimens (%) 678 (7.4%)
Positive specimens by type/subtype
Influenza A 567 (83.6%)
2009 H1N1 2 (0.4%)
H3 192 (33.9%)
Subytping not performed 373 (65.8%)
Influenza B 111 (16.4%)

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