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PostPosted: Wed Aug 27, 2014 7:02 pm 
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Media reports indicate the Ebola in the Democratic Republic of Congo is the Zaire strain.

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PostPosted: Wed Aug 27, 2014 7:06 pm 
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Posted on 27-08-2014 Edited on 27-08-2014 at 17:18
Ebola Zaire strain confirmed in DRC
by RFI

Six of the eight samples taken from patients in the Democratic Republic of Congo were positive to Ebola. Since August 11, 13 people died in a remote province of Ecuador about 800 miles northeast of Kinshasa sector. The IDRs confirmed that the strain of the disease in the DRC is the so-called "Zaire". Eric Leroy, Director of the International Centre for Medical Research, the laboratory in Franceville in Gabon who made the diagnosis, interviewed by RFI.

RFI: Your laboratory analyzed the samples taken from patients in the Democratic Republic of Congo. The results are determined, what are they?

Eric Leroy: Our laboratory was required as a WHO Collaborating Centre for diagnosing viral haemorrhagic fever and Ebola virus and therefore actually we confirmed the results obtained by Kinshasa and thus we confirmed the positive results in Ebola Zaire virus. For now we are at the stage of diagnosis, which is just to identify whether or not the Ebola within biological samples and to identify the virus species.

You know that the Ebola virus is divided into five species: Sudan, Zaire, Cote d'Ivoire, Bundibugyo and Reston and systems just allow us to differentiate the species. After the characterization of the strain itself, it is necessary to wait for the result of sequencing that is to say, the characterization of the entire genome sequence of the virus. Once the test has shown us that it was ZEBOV and now have a finer strain characterization, it is necessary to wait for the sequencing that we will get, hopefully, by weekend.

How many specimens exactly have you received and where do they come from?

We received eight biological samples that come from IRMB (National Institute for Biomedical Research in Kinshasa) who conducted the initial analyzes. The eight biological samples from eight patients obviously the affected area and the eight biological samples, we confirmed the presence of Ebola virus in six of them. The other two, it can be quite another disease because we must know expresses Ebola symptoms that are quite common in contrast to what people think and can be confused with many other diseases as a uncomplicated malaria, gastroenteritis and typhoid then. Finally, there are many other diseases like infection with Ebola virus.

Is that one can say that this strain is different when the same strain that currently grips West Africa?

As long as one does not have the result of sequencing, we can not be 100% positive, but given the context of the emergence of these cases, it is still very high probability that it is a different strain. It is a home that appeared in a small village so the movement of people between the small village of the DRC and Guinea is very, very unlikely. If the cases occurred in a big city, then we could actually raise the possibility of transmission of the strain. And there it is in a village, so it evokes a new appearance, a new emergence of the virus from an animal strain and therefore a strain different from Guinea.

Exactly how is it that the virus appears like that from time to time?

The virus can not live alone. He lives like a parasite, always within a living organism, it is called the reservoir. And numerous viruses, if not most of whom live within a living organism that is an animal, so it is called the "animal reservoir" so the natural host of the virus . And there he lives permanently, it does not appear, it does not disappear, it is always present. "The animal reservoir" carries a certain percentage. These animals naturally harbor the virus without getting sick.

And then with regard to the Ebola virus, are species of bat. So the virus is still there in populations of bats. By cons, it is not always there in the human species. The so-called outbreak of an epidemic or outbreak of a disease is when there is a transfer so a transmission from animals that hosts permanently virus to the species human. And conditions of this transmission are known, it is primarily in the butchering or handling of these animals, that the transfer or transmission may occur.

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