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PostPosted: Tue Feb 04, 2014 5:26 pm 
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Media confirming familial clusters for father daughter (37M/2F) and cousins (5M/4F).

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PostPosted: Tue Feb 04, 2014 5:26 pm 
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Reporters noted that in February 1, Huaiji County Zhaoqing pregnant towns reported a case of 5-year-old boy diagnosed with European H 7N 9 people infected with bird flu. This 4-year-old girls HUAIJI new cases of infection are reported association?

Yesterday, in an interview with reporters, the provincial CDC chief expert, Jianfeng, director of infectious disease prevention and control, said Town in Huaiji two children are cousins ​​relationship, this is a family cluster of cases, "Our survey found These two siblings living together, with the grandmother, on the top floor there are over 20 home raising chickens, including eight from just 10 days before the onset of the local market to buy back, raising chickens at home usually have the habit of New Year understood , the two children were fed together with her grandmother at home reared chickens, we detected in the top floor of the chicken house environment of H 7N 9 virus nucleic acid positive samples, and the two children with onset within the same incubation period, so you can basically determine two children exposed to the possibility of joint large, no evidence of efficient human-to-human transmission. "

Jianfeng said, there are family gathered together a pair of cases Zhongshan daughter, father Liang Yijun, 37, February 1 H 7N 9 confirmed human infection of bird flu; its half years old daughter diagnosed in February 2 H 7N 9 people infected with bird flu. Jianfeng said the investigation found that the father is doing barbecue, opportunities for joint exposure exists with her daughter, but is not yet able to rule out limited human to human transmission is possible.

http://news.ifeng.com/gundong/detail_20 ... 39_0.shtml

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PostPosted: Tue Feb 04, 2014 6:07 pm 
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niman wrote:
Reporters noted that in February 1, Huaiji County Zhaoqing pregnant towns reported a case of 5-year-old boy diagnosed with European H 7N 9 people infected with bird flu. This 4-year-old girls HUAIJI new cases of infection are reported association?

Yesterday, in an interview with reporters, the provincial CDC chief expert, Jianfeng, director of infectious disease prevention and control, said Town in Huaiji two children are cousins ​​relationship, this is a family cluster of cases, "Our survey found These two siblings living together, with the grandmother, on the top floor there are over 20 home raising chickens, including eight from just 10 days before the onset of the local market to buy back, raising chickens at home usually have the habit of New Year understood , the two children were fed together with her grandmother at home reared chickens, we detected in the top floor of the chicken house environment of H 7N 9 virus nucleic acid positive samples, and the two children with onset within the same incubation period, so you can basically determine two children exposed to the possibility of joint large, no evidence of efficient human-to-human transmission. "

Jianfeng said, there are family gathered together a pair of cases Zhongshan daughter, father Liang Yijun, 37, February 1 H 7N 9 confirmed human infection of bird flu; its half years old daughter diagnosed in February 2 H 7N 9 people infected with bird flu. Jianfeng said the investigation found that the father is doing barbecue, opportunities for joint exposure exists with her daughter, but is not yet able to rule out limited human to human transmission is possible.

http://news.ifeng.com/gundong/detail_20 ... 39_0.shtml

Zhongshan, Guangdong Zhaoqing now H7N9 family cluster of cases
http://news.sina.com.hk/news/20140205/-9-3181070/1.html

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PostPosted: Tue Feb 04, 2014 6:10 pm 
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niman wrote:
niman wrote:
Reporters noted that in February 1, Huaiji County Zhaoqing pregnant towns reported a case of 5-year-old boy diagnosed with European H 7N 9 people infected with bird flu. This 4-year-old girls HUAIJI new cases of infection are reported association?

Yesterday, in an interview with reporters, the provincial CDC chief expert, Jianfeng, director of infectious disease prevention and control, said Town in Huaiji two children are cousins ​​relationship, this is a family cluster of cases, "Our survey found These two siblings living together, with the grandmother, on the top floor there are over 20 home raising chickens, including eight from just 10 days before the onset of the local market to buy back, raising chickens at home usually have the habit of New Year understood , the two children were fed together with her grandmother at home reared chickens, we detected in the top floor of the chicken house environment of H 7N 9 virus nucleic acid positive samples, and the two children with onset within the same incubation period, so you can basically determine two children exposed to the possibility of joint large, no evidence of efficient human-to-human transmission. "

Jianfeng said, there are family gathered together a pair of cases Zhongshan daughter, father Liang Yijun, 37, February 1 H 7N 9 confirmed human infection of bird flu; its half years old daughter diagnosed in February 2 H 7N 9 people infected with bird flu. Jianfeng said the investigation found that the father is doing barbecue, opportunities for joint exposure exists with her daughter, but is not yet able to rule out limited human to human transmission is possible.

http://news.ifeng.com/gundong/detail_20 ... 39_0.shtml

Zhongshan, Guangdong Zhaoqing now H7N9 family cluster of cases
http://news.sina.com.hk/news/20140205/-9-3181070/1.html

http://www.zjkonline.com/zjk_jieguo.asp?newsid=636470

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PostPosted: Tue Feb 04, 2014 7:29 pm 
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Commentary

http://www.recombinomics.com/News/02041 ... ilial.html

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PostPosted: Wed Feb 05, 2014 12:40 pm 
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Two of the cases are male. The age range is 2 to 76 years old. Cases were reported from Guangdong (2), Hunan (1) and Fujian (1). One case is currently in a serious condition, one is in a critical condition, one is in a mild condition. All cases are reported to have had a history of exposure to poultry or a live poultry market.
A 27 year-old man from Zhangzhou City, Fujian Province, who became ill on 21 January and admitted to hospital on 31 January. He is currently in a critical condition. The patient has a history of exposure to a live poultry market.
A 59 year-old man from Loudi City, Hunan Province, who became ill on 23 January and was admitted to hospital on 31 January. He died on 3 February. The patient had a history of exposure to live poultry market.
A 2 year-old female from Zhongshan City, Guangdong Province, who became ill on 31 January and was admitted to hospital on the same day. She is currently in a mild condition. The patient has a history of exposure to live poultry and a live poultry market.
A 76 year old woman from Huizhou City, Guangdong Province, who became ill on 27 January and was admitted to hospital on 1 February. She is currently in a serious condition. The patient has a history of exposure to live poultry.



So far, there is no evidence of sustained human-to-human transmission.

The Chinese Government continues to take the following surveillance and control measures:
strengthen surveillance and situation analysis;
reinforce case management and treatment;
conduct risk communication with the public and release information;
strengthen international collaboration and communication; and
conduct scientific studies.

Sporadic human cases

While the recent report of avian influenza A(H7N9) virus being detected in live poultry imported from the mainland to Hong Kong SAR, shows the potential for the virus to spread through live poultry, at this time there is no indication that international spread of avian influenza A(H7N9) has occurred through humans or animals.

Further sporadic human cases of A(H7N9) infection are expected in affected and possibly neighbouring areas, especially given expected increases in the trade and transport of poultry associated with the Lunar New Year.

WHO advice

WHO advises that travellers to countries with known outbreaks of avian influenza should avoid poultry farms, or contact with animals in live bird markets, or entering areas where poultry may be slaughtered, or contact with any surfaces that appear to be contaminated with faeces from poultry or other animals. Travellers should also wash their hands often with soap and water. Travellers should follow good food safety and good food hygiene practices.

WHO does not advise special screening at points of entry with regard to this event, nor does it currently recommend any travel or trade restrictions.

As always, a diagnosis of infection with an avian influenza virus should be considered in individuals who develop severe acute respiratory symptoms while travelling or soon after returning from an area where avian influenza is a concern.

WHO encourages countries to continue strengthening influenza surveillance, including surveillance for severe acute respiratory infections (SARI) and to carefully review any unusual patterns, in order to ensure reporting of human infections under the IHR (2005), and continue national health preparedness actions.



Current technical information as well as guidance related to avian influenza A(H7N9) can be found at the WHO web site:
Avian influenza A(H7N9) virus
Human infections with avian influenza A(H7N9) virus
pdf, 194kb
21 January 2014
World - Avian influenza in humans
Live food markets: Reducing the risk of influenza virus transmission from animals

http://www.who.int/csr/don/2014_02_05/en/index.html

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PostPosted: Wed Feb 05, 2014 1:48 pm 
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5 February 2014 - On 4 February 2014, the National Health and Family Planning Commission (NHFPC) of China notified WHO of eight additional laboratory-confirmed cases of human infection with avian influenza A(H7N9) virus, including two deaths. .


Details of the cases are as follows

Six of the cases are male. The age range is 4 to 84 years old. Cases were reported from Zhejiang (4), Guangdong (3) and Jiangsu (1). Three cases are currently in a critical condition, two cases are currently in a severe condition and one is currently in a mild condition. All cases are reported to have had a history of exposure to poultry or a live poultry market.
A 42 year-old man from Hangzhou City, Zhejiang Province, who became ill on 25 January and was admitted to hospital on 30 January. He is currently in a severe condition. The patient has a history of exposure to poultry.
An 84 year-old man from Hangzhou City, Zhejiang Province, who became ill on 24 January and was admitted to hospital on 28 January. He is currently in a critical condition. The patient has a history of exposure to poultry.
A 56 year-old man from Jinhua City, Zhejiang Province, who became ill on 24 January and was admitted to hospital on 1 February. He is currently in a severe condition. The patient has a history of exposure to a live poultry market.
A 51 year-old man from Shaoxing City, Zhejiang Province, who became ill on 27 January and was admitted on 1 February. He is currently in a critical condition. The patient has history of exposure to a live poultry market.
A 4 year-old girl from Zhaoqing City, Guangdong Province, who became ill on 26 January and was admitted to hospital on 3 February. She is currently in a mild condition. The patient has a history of exposure to live poultry.
A 76 year-old man from Yangjiang City, Guangdong Province, who became ill on 27 January and was admitted to hospital on 1 February. He died on 3 February. The patient had a history of exposure to live poultry.
A 52 year-old man from Huizhou City, Guangdong Province, who became ill on 25 January and was admitted to hospital on 2 February. He died on 3 February. The patient had a history of exposure to live poultry.
A 59 year-old woman from Wuxi City, Jiangsu Province, who became ill on 26 January and was admitted to hospital on 29 January. She is currently in a critical condition. The patient has history of exposure to a live poultry market.



So far, there is no evidence of sustained human-to-human transmission.

The Chinese Government continues to take the following surveillance and control measures:
strengthen surveillance and situation analysis;
reinforce case management and treatment;
conduct risk communication with the public and release information;
strengthen international collaboration and communication; and
conduct scientific studies.

Sporadic human cases

While the recent report of avian influenza A(H7N9) virus being detected in live poultry imported from the mainland to Hong Kong SAR, shows the potential for the virus to spread through live poultry, at this time there is no indication that international spread of avian influenza A(H7N9) has occurred through humans or animals.

Further sporadic human cases of A(H7N9) infection are expected in affected and possibly neighbouring areas, especially given expected increases in the trade and transport of poultry associated with the Lunar New Year.

WHO advice

WHO advises that travellers to countries with known outbreaks of avian influenza should avoid poultry farms, or contact with animals in live bird markets, or entering areas where poultry may be slaughtered, or contact with any surfaces that appear to be contaminated with faeces from poultry or other animals. Travellers should also wash their hands often with soap and water. Travellers should follow good food safety and good food hygiene practices.

WHO does not advise special screening at points of entry with regard to this event, nor does it currently recommend any travel or trade restrictions.

As always, a diagnosis of infection with an avian influenza virus should be considered in individuals who develop severe acute respiratory symptoms while travelling or soon after returning from an area where avian influenza is a concern.

WHO encourages countries to continue strengthening influenza surveillance, including surveillance for severe acute respiratory infections (SARI) and to carefully review any unusual patterns, in order to ensure reporting of human infections under the IHR (2005), and continue national health preparedness actions.



Current technical information as well as guidance related to avian influenza A(H7N9) can be found at the WHO web site:
Avian influenza A(H7N9) virus
Human infections with avian influenza A(H7N9) virus
pdf, 194kb
21 January 2014
World - Avian influenza in humans
Live food markets: Reducing the risk of influenza virus transmission from animals


http://www.who.int/csr/don/2014_02_05bis/en/index.html

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PostPosted: Wed Feb 05, 2014 7:05 pm 
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Commentary

http://www.recombinomics.com/News/02051 ... F_WHO.html

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PostPosted: Wed Feb 05, 2014 9:14 pm 
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No H7N9 letup as Guangxi detections prompt warning

Lisa Schnirring | Staff Writer | CIDRAP News | Feb 05, 2014

China reported nine new H7N9 influenza cases today, including the third from Guangxi province, signaling a rise in disease activity in a region that borders Vietnam along with the first reports of poultry market detections there, according to a warning today from an animal health group.

The other eight new cases are from two provinces—Guangdong and Zhejiang—that are reporting the largest portion of cases in the second wave, which has now eclipsed the first wave by a growing margin. So far 174 cases have been reported in the outbreak's second wave, compared to 136 recorded during the first spike in disease activity last spring.

Nine cases from three provinces

Zhejiang province reported four case-patients, including a 67-year-old man in severe condition, a 49-year-old man in critical condition, and two women, ages 35 and 59, who are hospitalized in severe condition, according to official statements translated and posted by Avian Flu Diary (AFD), an infectious disease news blog, and FluTrackers, an infectious disease message board.

Guangdong province also reported four cases, in a 5-year-old girl and a 49-year-old man listed in stable condition and in two men, ages 42 and 56, who are hospitalized in critical condition, according to official notices posted by AFD and FluTrackers.

The case from Guangxi province is in a 5-year-old boy who is in stable condition. The boy's infection marks the third from the province, a mountainous area located southwest of the main outbreak hot spots, notable because it borders northern Vietnam.

The boy got sick a day after an H7N9 infection was confirmed in his 41-year-old mother, the South China Morning Post (SCMP), an English-language newspaper based in Hong Kong, reported today.

The new cases raise the outbreak total to 310 cases since last February, according to a running tally maintained by FluTrackers. The unofficial fatality count remained at 67.

Health officials are investigating the source of the boy's infection and noted that he had been in close contact with his mother, who is hospitalized in critical condition, according to the SCMP report. The two infections mark the second known H7N9 family cluster during the second wave of infections.

So far, human-to-human spread in those two events hasn't been confirmed, and health officials are exploring if the patients had the same poultry exposure. The World Health Organization (WHO) has said limited human-to-human spread wouldn't be surprising, especially in people who had prolonged unprotected contact. However, the agency said there is still no evidence of sustained H7N9 transmission.

WHO reports strong poultry exposure risk

The disease seems to be spreading primarily from poultry or their environments to people, a point underscored by two WHO updates today that provided additional details on 12 case reports it received from China on Feb 3 and Feb 4. All 12 of the patients had been exposed to poultry or live-poultry markets.

The 12 cases described in the WHO reports span five different provinces: Guangdong (5), Zhejiang (4), and one each from Fujian, Hunan, and Jiangsu. Three deaths are included in the WHO's report, in a 59-year-old man from Hunan province, a 76-year-old man from Guangdong, and a 52-year-old man from Guangdong.

Patient ages range from 2 to 84, and illness onsets range from Jan 21 to Jan 27. Of the nine survivors, four are in critical condition, three are in severe condition, and two have mild infections.

The two patients who have mild cases are both girls, one 2 years old and one 4 years old. So far the disease in children has been mild compared with adults—especially older ones—who often experience rapidly progressing severe pneumonia.

FAO sounds alarm over Guangxi market detections

In other H7N9 developments today, the United Nations Food and Agriculture Organization (FAO) today warned that the spread of the virus in Guangxi province's live-bird markets poses an increasing threat to Vietnam and China's other neighbors, according to a statement posted on the group's Asia and Pacific regional office Web site.

Chinese officials found the virus in live-bird markets in Guangxi between Jan 24 and Jan 28 in an area where the province's first human case was detected, the FAO said. It emphasized that Guangxi shares a border with Vietnam, and neighboring Yunnan province shares a border with Myanmar, Laos, and Vietnam.

The FAO said it has been working closely with Vietnam since June 2013 to support H7N9 surveillance in more than 60 live-bird markets in the northern part of the country.

"So far, there is no evidence that the virus is present in Vietnam or any of China's other neighboring countries in Southeast Asia," the group said. "But there are indications, based on previous experience with the H5N1 virus, that H7N9 is easily capable of circulating across borders."

The flow of poultry between China and its neighbors, combined with the possible economic impact of an outbreak, elevates H7N9 as a serious public health risk, especially during festival times, such as during the nation's current Lunar New Year celebrations, the FAO said.

Hiroyuki Konuma, the FAO's assistant director-general, in the statement urged countries in the region to review their response plans, boost surveillance, and raise awareness of the H7N9 threat. "Urgent initiatives are needed to improve biosecurity in live bird markets, and a clear response plan to disrupt the transmission cycle of the virus in case of an incursion is also necessary," he said.

The latest on poultry testing, control measures

Meanwhile, the WHO's Western Pacific Regional Office (WPRO) today provided a situation update on H7N9 disease activity from Jan 24 to Jan 31, including the results of the latest poultry testing, along with surveillance and control measures, according to reports from Chinese officials.

It said that so far this year, 33,400 samples have been collected, and eight were positive for H7N9. The virus was detected in five live-bird markets in four provinces: Guangdong, Fujian, Guangxi, and Zhejiang.

Among the latest control measures, Zhejiang province, which has recorded the most human cases, on Jan 28 said all live-animal markets in major cities and districts will be closed until Feb 15. Officials added that live-poultry markets in cities' main district areas will be permanently shuttered as of Jul 1.

The WHO statement also said Fujian province on Jan 20 temporarily suspended the transport of live poultry from areas outside its border.

See also:

Feb 5 AFD post

Feb 5 FluTrackers thread on today's cases

FluTrackers H7N9 human case count

Feb 5 SCMP story

Feb 5 WHO statement on Feb 3 reports from China

Feb 5 WHO statement on Feb 4 reports from China

Feb 5 FAO statement

Feb 5 WHO WPRO situation update

http://www.cidrap.umn.edu/news-perspect ... pt-warning

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PostPosted: Thu Feb 06, 2014 8:03 am 
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Original title: Zhongshan, Guangdong first case of H7N9 bird flu patient out of danger after emergency treatment

BEIJING, Feb. 6, Zhongshan Power (Dengyuan Wen Chen Yanru) reporter on the 6th publicity from Triangle Town, Zhongshan City Office was informed that the town is being two H7N9 patients treatment, a few days before the 37-year-old patient in critical condition, doctors have identified the 6th "There is no danger."

According to Triangle Town Lianglian Ying, deputy director of publicity office, the town appeared in the first case of familial aggregation of cases, the patient is a father and daughter, 37-year-old father LiangMou on February 1 confirmed human infection of H7N9 avian influenza, which half years old daughter in February 2 was diagnosed with the case.

According Lianglian Ying introduced the day before the specified isolation and treatment of Zhongshan Hospital treating physician has revealed that 37-year-old patient was in critical condition, "spent two days if there is no danger," and returned from the hospital today, the good news, the patient out of danger, his daughter also achieved some therapeutic effect.

It is reported that patients Yijun and his wife run a town in Zhongshan Triangle meat shop, whenever buy chickens from live bird markets, Liang Yijun will be processed into chicken sales.

Lianglian Ying, currently three birds Triangle town market has closed seven days, the town of relevant departments to buy a batch of disinfectant, for three consecutive days to disinfect the bird market, and thus the village, neighborhood disinfect Triangle hospitals and health stations for more than 37.5 degrees or more patients were persuaded to Zhongshan City People's Hospital and other major hospitals clinics, collecting swabs testing. It is reported that the health sector has been on Zhongshan close contacts under medical observation, yet found an exception. (End)

http://dailynews.sina.com/bg/chn/chnpol ... 30923.html

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