hours ago
PB1-F2 is mainly truncated in humans,swine,poultry while most wild birds
have a full PB1-F2. After some time of evolution outside wild birds
it may become reduced in length or get disfunctional.
http://www.setbb.com/fluwiki2/viewtopic.php?p=1901So apparantly it is important in wild birds but not in mammals, poultry.
Where are poultry different from wild birds ? Anatomy is the same, so
presumably it's the way of living, the spread of the virus.
For wild birds fecal-oral is important while for mammals,poultry it's
repiratory ? For wild birds it spreads by flying. Someone please test
why a truncated PB1-F2 is bad for wild birds ...
Now, the idea is to help the virus a bit, truncate PB1-F2 in humans so it
spreads better and outcompetes old H3N2 (if mexflu should fail to do this...)
but at the same time also becomes less virulent.
Hey, the idea is to create a flu as mild as a cold :-) but also as frequent :-(
Flu alone is not so much interested to do this, if we don't help it,
it's just interested in wild birds, where it reassorts like crazy