Rhiza Labs FluTracker Forum

The place to discuss the flu
It is currently Sun Oct 22, 2017 4:58 pm

All times are UTC - 5 hours [ DST ]




Post new topic Reply to topic  [ 91 posts ]  Go to page Previous  1, 2, 3, 4, 5, 6, 7, 8 ... 10  Next
Author Message
PostPosted: Wed Sep 02, 2009 3:24 pm 
Offline

Joined: Wed Aug 19, 2009 10:42 am
Posts: 56044
Location: Pittsburgh, PA USA
Shasta123 wrote:
wotan wrote:
niman wrote:
Here is another denial

Specious Report of Bird and Swine Flu Co-infection
An Egyptian news story that is starting to receive worldwide attention about a nightmare swine flu/bird flu co-infection is inaccurate, according to officials at the U.S. Centers for Disease Control and Prevention (CDC).

On 30 August, the well regarded Egyptian newspaper Almasry reported that an Egyptian man who returned from a religious pilgrimage to Saudi Arabia had tested positive for both the highly lethal bird flu virus, H5N1, and the novel H1N1 strain that’s behind the swine flu pandemic. This is the first such report of a co-infection with the two viruses, which many researchers fear because the mix could create a new virus that has the virulence of bird flu, which does not move easily between humans, and the highly transmissible swine flu.

The Egyptian report was picked up yesterday by the widely read electronic surveillance system ProMED. Although the ProMED moderators raised many questions about the story, it remained unclear whether it was accurate. According to Nancy Cox, head of the CDC’s influenza division, there’s no evidence that this man is infected with both viruses. “Our reliable sources indicate that this report is incorrect,” Cox told ScienceInsider in an e-mail. Apparently, tests have shown that the man is coinfected with the pandemic H1N1 and the seasonal H3N2 virus. “There will be follow up testing to confirm,” according to Cox. As many as 5% of people who develop flu symptoms are infected with two different influenza viruses.

—Jon Cohen
http://blogs.sciencemag.org/scienceinsi ... eport.html


This looks to me like the original report we saw yesterday, rather than the 3 new cases from today.

Yes, this only appears to mention the one case and not 3.

Commentary is attracting interest

http://www.newsnow.co.uk/h/Hot+Topics/Swine+Flu?type=ts

_________________
www.twitter.com/hniman


Top
 Profile  
 
PostPosted: Wed Sep 02, 2009 3:24 pm 
Offline
User avatar

Joined: Wed Aug 19, 2009 10:12 pm
Posts: 1283
Nancy Cox seems to be referring to the one patient whose test turned out negative, not the rest of the suspected co-transmission patients. (2 in Hurghada, 1 in Safaga, 5 (or is it 7...isn't clear) in Mansoura

From one of the source stories:
Quote:
A 28-year-old man that arrived at the port of Safaga after visiting Saudi Arabia was confirmed as infected by the bird flu and swine flu (H5N1 avian influenza and the pandemic H1N1 respectively).

The man was immediately detained after confirmation and isolated in a hospital in Hurghada.

The director-general of preventive medicine, Mohammad Rifai stated that this case is the third found in 2 days.

The other two cases involve a 35-year-old Italian tourist that is also being retained in Hurghada and a 30-year-old pilgrim that was detained in Safaga Central Hospital.

A fourth sample from a 38-year-old was taken but tested negative.

Two other suspected cases with similar illnesses have been held in Mansoura fever hospital.

Another five cases, from which four are children, are also being held in Mansoura Chest hospital after suspicions of having both virus infections.


http://www.ubalert.com/a/9452


Top
 Profile  
 
PostPosted: Wed Sep 02, 2009 3:30 pm 
Offline
User avatar

Joined: Tue Aug 11, 2009 2:58 pm
Posts: 1419
Location: Katy, TX
MKey1 wrote:
Nancy Cox seems to be referring to the one patient whose test turned out negative, not the rest of the suspected co-transmission patients. (2 in Hurghada, 1 in Safaga, 5 (or is it 7...isn't clear) in Mansoura

From one of the source stories:
Quote:
A 28-year-old man that arrived at the port of Safaga after visiting Saudi Arabia was confirmed as infected by the bird flu and swine flu (H5N1 avian influenza and the pandemic H1N1 respectively).

The man was immediately detained after confirmation and isolated in a hospital in Hurghada.

The director-general of preventive medicine, Mohammad Rifai stated that this case is the third found in 2 days.

The other two cases involve a 35-year-old Italian tourist that is also being retained in Hurghada and a 30-year-old pilgrim that was detained in Safaga Central Hospital.

A fourth sample from a 38-year-old was taken but tested negative.

Two other suspected cases with similar illnesses have been held in Mansoura fever hospital.

Another five cases, from which four are children, are also being held in Mansoura Chest hospital after suspicions of having both virus infections.


http://www.ubalert.com/a/9452


Eh? It seems to be snowballing. Hopefully a truthful answer will be forthcoming, and that right soon.

Does anyone else see an irony in the "doomsday scenario" coming out of the middle east?

_________________
I am not a doctor, virologist, or any of type of medical/life sciences professional.

I am a layman with a background in the physical sciences.


Top
 Profile  
 
PostPosted: Wed Sep 02, 2009 3:38 pm 
Offline

Joined: Wed Aug 19, 2009 12:00 pm
Posts: 712
VJP wrote:
In other "words":
:confused:
:shock:
:scratch:
:(
:worried:


:banghead: >>> (That's @ the conflicting reports, not you).

Adding to your list ;) Hopefully we will get concrete answers soon.


Last edited by Faithful on Wed Sep 02, 2009 5:05 pm, edited 1 time in total.

Top
 Profile  
 
PostPosted: Wed Sep 02, 2009 4:46 pm 
Offline

Joined: Wed Aug 19, 2009 10:42 am
Posts: 56044
Location: Pittsburgh, PA USA
There seem to be a large number of suspect cases.


Top
 Profile  
 
PostPosted: Wed Sep 02, 2009 4:54 pm 
Offline

Joined: Wed Aug 19, 2009 12:00 pm
Posts: 712
niman wrote:
There seem to be a large number of suspect cases.


Oh dear :( Not good.

Can you elaborate on an approximate amount of people?? Thanks, Dr.Niman.


Top
 Profile  
 
PostPosted: Wed Sep 02, 2009 5:02 pm 
Offline

Joined: Wed Aug 19, 2009 10:29 pm
Posts: 128
Yes, please elaborate, a lot of us are watching and waiting to find out something.

I'm surprised we're not seeing more internet activity regarding what potentially could be a nightmare.


Top
 Profile  
 
PostPosted: Wed Sep 02, 2009 6:49 pm 
Offline

Joined: Fri Aug 28, 2009 12:19 am
Posts: 108
If this is a double post, please delete
http://www.pressweb.it/09/02/primi-casi ... a-n5h1.htm
Google translation:
In Egypt in Cairo and have been receive 3 men, including a 35 year old Italian, in which the tests have detected the simultaneous presence of the virus A/N1H1 and Avian Influenza virus A/N5H1, all three men are currently under strict isolation and monitored closely to study the progression of infection and the effect of the treatment is administered.
According to a statement by Mohammad Rifai, Managing Director of Preventive Medicine, the three cases occurred in the last two days, while others, including 4 children, were hospitalized in various hospitals in the area with the suspicion of having the same two viruses.
If confirmations are received on this double infection there will be a further reason for concern and should be reviewed all the plans to combat influenza A in the light also of a search for a new vaccine to fight this infection further.

original text http://www.pressweb.it/09/02/primi-casi ... a-n5h1.htm


Top
 Profile  
 
PostPosted: Wed Sep 02, 2009 7:18 pm 
Offline

Joined: Thu Aug 20, 2009 5:23 am
Posts: 20
niman wrote:
niman wrote:
David Rousseau wrote:
i agree with that

but
Dr. Niman, how many cases at least be there for that possible reassortment is a threat?

Co-transmission is a bigger threat than reassortment or recombination.

Co-transmission would mean that H5N1 is efficiently transmitted H2H by hitching a ride with pandemic H1N1 which appears to be able to infect everything (humans, swine, turkeys, and much more).

The only thing that H5N1 was missing to become a major pandemic was efficient H2H transmission, which would be solved via co-transmission.

Moreover, if this is transmitting in Saudi Arabia among pilgrims, they will spread the combo worldwide as they return to their country of origin.

This really is a perfect storm if these two viruses are co-transmittting.





I was gone.
Dr. Niman thank you for that explanation!


Top
 Profile  
 
PostPosted: Wed Sep 02, 2009 7:40 pm 
Offline

Joined: Wed Aug 19, 2009 10:42 am
Posts: 56044
Location: Pittsburgh, PA USA
Here is an update from ProMed, which essentially repeats earlier denials

H5N1/H1N1 VIRUS CO-INFECTION - EGYPT (02): ex SAUDI ARABIA, NOT
***************************************************************
A ProMED-mail post
<http://www.promedmail.org>
ProMED-mail is a program of the
International Society for Infectious Diseases
<http://www.isid.org>


Date: Tue 1 Sep 2009
Source: Youm7 [in Arabic, machine trans., edited]
<http://www.youm7.com/News.asp?NewsID=132676>

The Ministry of Health through the Council of Ministers daily report
on the situation regarding swine flu [pandemic (H1N1) 2009 influenza
virus infection], has now discounted the rumour of [a co-infection]
with avian influenza virus of one of the cases infected with H1N1 type
virus upon his arrival at the port of Safaga from Umrah [pilgrimage to
Saudi Arabia].

The Ministry said that this pilgrim was infected with swine flu
[pandemic (H1N1) 2009 virus] in addition to a common [seasonal] flu
and not bird flu [avian H5N1 influenza virus]. [Previously it was
suggested that the patient was co-infected with H1N1 and H5N1 viruses.
- Mod.CP]. This patient's health is good and his condition stable. He
will leave hospital within 2 days after treatment. This emphasizes the
lack of any potential interaction between a mutant avian H5N1 virus in
Egypt and an H1N1 strain.
[Byline: Mona Zia]
--
Communicated by:
ProMED-mail Rapporteur Mary Marshall

******
Date: Wed, 2 Sep 2009 11:44:45 -0500 [12:44:45 EDT]
From: Jason Garner <jasonlgarner@gmail.com>

I would like to pass on information just released by both PLoS and the
NIH regarding interaction of the pandemic A(H1N1) with co-infections
of seasonal flu viruses.

A University of Maryland/NIH study, using ferret animal models,
suggests that co-infections of A(H1N1) with seasonal flu viruses do
not produce chimeric or reassortant viruses. Said another way, the
A(H1N1) outcompetes seasonal viruses, possibly demonstrating the
pandemic strain is not under biological pressure and is perhaps more
efficiently communicable.

However, with regard to the H5N1-A(H1N1) co-infections reported
recently, there is no data to suggest these latest findings could
apply to H5N1 co-infections. In light of the characteristic that HPAI
H5N1 has been shown to be a "dead-end" infection in humans, it could
possibly be out-competed by a more robust strain such as A(H1N1)
rather than being a player in a recombination event.

Link to the NIH study results summary:
<http://www.nih.gov/news/health/aug2009/niaid-31.htm>

--
Jason L Garner
Senior Molecular Biologist
Global Influenza Surveillance

*******
Date: Wed, 2 Sep 2009
From: Mary Marshall <mjm2020@googlemail.com>
Source: ScienceInsider
<http://blogs.sciencemag.org/scienceinsider/2009/09/specious-report.html>

Specious Report of Bird and Swine Flu Co-infection
--------------------------------------------------
An Egyptian news story that is starting to receive worldwide attention
about a nightmare swine flu/bird flu co-infection is inaccurate,
according to officials at the U.S. Centers for Disease Control and
Prevention (CDC).
On 30 August, the well-regarded Egyptian newspaper Almasry reported
that an Egyptian man who returned from a religious pilgrimage to Saudi
Arabia had tested positive for both the highly lethal bird flu virus,
H5N1, and the novel H1N1 strain that is the cause of the swine flu
pandemic.

This was the first such report of a co-infection with the two viruses,
which many researchers fear because the mix could create a new virus
that has the virulence of bird flu, which does not move easily between
humans, and the highly transmissible swine flu.

The Egyptian report was picked up yesterday by the widely read
electronic surveillance system ProMED. Although the ProMED moderators
raised many questions about the story, it remained unclear whether it
was accurate. According to Nancy Cox, head of the CDC?s influenza
division, there is no evidence that this man is infected with both
viruses. ?Our reliable sources indicate that this report is
incorrect,? Cox told ScienceInsider in an e-mail. Apparently, tests
have shown that the man is co-infected with the pandemic H1N1 and the
seasonal H3N2 virus. ?There will be follow up testing to confirm,?
according to Cox. As many as 5% [1 in 20] people who develop flu
symptoms are infected with 2 different influenza viruses.
[By Jon Cohen]

[The statement from the Egyptian Ministry of Health denies the
earlier report that a pilgrim returned from Saudi Arabia was infected
with both pandemic H1N1 influenza virus and an avian (H5N1) influenza
virus strain.
It now appears that the co-infection is believed to be between 2 low
virulence viruses (pandemic H1N1 & H3N2) and *not* between a highly
virulent, poorly transmissible, virus (pandemic H1N1) and a highly
transmissible strain of low virulence (H5N1) which might, as a result
of genetic interaction, generate a highly transmissible and highly
virulent strain. The consequences of the interaction as a result of
co-infection of 2 highly transmissible viruses of low to moderate
virulence, as in the present case, are unclear but less threatening.

A question arises over the accuracy of the diagnostic procedures
supporting the claim of co-infection. A highly relevant comment on the
original report from Egypt has been received from Jason L Garner,
Senior Molecular Biologist, Global Influenza Surveillance
(<jasonlgarner@gmail.com>) and is reproduced in full below.

"This is a worrisome event.
1) My 1st and obvious question is how were these results obtained? DFA
[direct fluorescence antibody]? RT-PCR? rRT-PCR?
2) Also, what type of specimen was used in the assay, such as NP
[nasopharyngeal], nasal wash, throat swab, virological culture? Unlike
seasonal or pandemic A (H1N1) flu, the preferred method for collecting
HPAI H5N1 specimens is via throat swab, and the others either NP or
nasal wash. From a molecular standpoint HPAI H5N1 is difficult to
discern even in sensitive rRT-PCR assays, unless an original throat
swab and/or a cultured isolate was employed.
3) If it was obtained with cultured isolate, wouldn't one strain
perhaps out-compete the other as is usually the case with seasonal H1
and H3 viruses?
4) Are there substantial differences in LPAI and HPAI gene segment
targets to discern with assay used?
5) Lastly, how and by what methods, if any, were potential
contamination variables controlled?
Very interested to learn more."

A response from the Egyptian Ministry of Health would be welcomed. -
Mod.CP/JW]

[see also:
H5N1/H1N1 virus co-infection - Egypt: ex S.Arabia, susp, RFI 20090901.3081]
........................................cp/mj/jw

_________________
www.twitter.com/hniman


Top
 Profile  
 
Display posts from previous:  Sort by  
Post new topic Reply to topic  [ 91 posts ]  Go to page Previous  1, 2, 3, 4, 5, 6, 7, 8 ... 10  Next

All times are UTC - 5 hours [ DST ]


Who is online

Users browsing this forum: No registered users and 45 guests


You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum
You cannot post attachments in this forum

Search for:
Jump to:  
cron
Powered by phpBB® Forum Software © phpBB Group