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http://www.recombinomics.com/News/05131 ... y_CDC.html

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This is an article about a Porcine reproductive and respiratory syndrome virus (PRRSV) -- in pigs -- in Korea --
caused severe pneumonia

http://7thspace.com/headlines/379443/ex ... _pigs.html

Experimental infection of a newly emerging Korean type I porcine reproductive and respiratory syndrome virus isolate in colostrum-deprived pigs


Recently, new emergence of type I PRRSV has been reported in Korea by several research groups. Although specific subgroups of type I PRRSVs in Korea were observed in the previous phylogenetic analysis, there is a lack of information about the virulence of type I PRRSV recently isolated in Korea.

Methods: One type I PRRSV isolate (G2446, 3 times passaged in primarily cultured pulmonary macrophages) in Korea was experimentally infected in colostrum-deprived pigs.

The pathological and serological evaluations were performed and compared to type II PRRSV strain (CP07-401-9, 5 times passaged in MARC-145 cell lines)-infected pigs, for 21 days post challenge (dpc).

Results: The pneumonia found in gross examination was more severe in type I PRRSV-infected pigs than type II PRRSV-infected pigs. Both groups showed bronchointerstitial pneumonia, mild multifocal perivascular lymphohistiocytic myocarditis and lymphadenopathy at 14 dpc.

However, the unique histopathologic lesions were not found in the pigs experimentally infected with a Korean type I PRRSV isolate, when compared to previous data about classical pathology of PRRSV. The PRRS-specific antibodies were detected in the first week after challenge and viremia continued at least until 21 dpc in both groups.

Conclusion: The gross and histopathologic lesion in this study indicated that Korean type I PRRSV strain (G2446) caused classical PRRSV-specific lesions.

Although this study evaluated one representative strain of Korean type I PRRSV, the results may provide information regarding the pathogenicity of type I PRRSV recently emerged in Korea.

Author: Hye Kwon KimChul Seung LeeBo Kyu KangMin Ju YeomHyoung Joon MoonSeong Jun ParkVan Giap NguyenDae Sub SongBong Kyun Park
Credits/Source: Virology Journal 2011, 8:177



Published on: 2011-04-17

The Korean CDC has already acknowledge that the infection was due to a flu virus that has been isolated. PRRSV is not a flu virus, and sequencing of a PRSSV isolate from a human would not address the cause of death (sequencing is being done to determine the pressence of D225N).

There is no credible source denying that the "mystery" flu virus is H1N1 (and the linkage of pandemic H1N1 with pregnant cases is well known).

PRRSV, pneumonia, and Korea is just an irrelevant Google result.

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Thought that was likely ... but I hope they do give an update on the situation in Korea today.

It ia already 10 PM on Friday in Korea. The update was suppose to be on Thursday. They may be planning a weekend news dump to limit discussion. I can't see the CDC calling something other than influenza a flu virus, and flu in 7/8 pregnant patients would be H1N1.

The real question is if it is Chihuahua and has D225N, both of which are HIGHLY likely.

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a posting by alert at FTs .....

http://www.flutrackers.com/forum/showth ... post408271

Apparently the testing ongoing is to sequence the adenovirus 53 that has been isolated from one patient and to determine whether it contains any mutations. It is still unclear whether this adenovirus is the cause of this whole outbreak.

If the patients did not have contact with each other, and took ill over several weeks or more, there is no guarantee they were all infected by the same thing.

http://www.yonhapnews.co.kr/society/...200900017.HTML

Unidentified pneumonia, pathogens Inspection Questions and Answers>

(AP) Kim Sang Hun, Centers for Disease Control press = 11 days and using samples from patients with pneumonia of unknown pathogen test results to the disease influenza is difficult to see that you have concluded that.

The following test results were released today yangbyeongguk Centers for Disease Control Infectious Disease Q & A with Director of Administration.


- 20 kinds of pathogens, there is no influenza test only conclude that if you can.

▲ 20 가지 pathogen prediction by examining all possible checks are carried out for bacterial viruses. There is no need to further examine. Virus is difficult to say at all that the average two weeks after the onset of sampling, a dalgaryangyi has been made in the past when there is a limit.

- Got off to the conclusion that infectious.

▲ contagious to the other patients around occurs. However, in addition to the 8 patients were found in the other patients with a wide range of occurrence in the region did not materialize. Than women at the elderly and patients with weakened immune systems are also not to come. Thus, a very high infectivity or neurological health problems than the level is expected to be.

- A medical doctor to check hazards as clinically sickle.

▲ The new disease, pneumonia was found in the debate was about whether. Among infectious diseases, we all like to get outside for an unspecified number of infections to the edification of the disease is managed. Until today, I have your attention, such as epidemiology and pathogens that were tested. More than one pathogen testing unnecessary in situations with individual patients is necessary to identify the characteristics. In the case of hospital inpatient hospital staff and decided to check hayeogeum We will actively support them.

- What Is further testing to proceed.

▲ currently listed for adenovirus 53 DNA tests to check whether it is genetically modified. Injected into animals or cultured virus induced lesions, and these lesions in patients examined to determine whether a match will be held.

- To the past, children had the onset of acute interstitial pneumonia compared with pneumonia and if this.

▲ If the patient's symptoms of pneumonia, wonder about how to proceed, such as X-rays and CT radiography imaging findings, pathologic findings of lung tissue and microbiological test results from diseases such as can be seen if they match. Reported in the past year when contrasted with pneumonia-related data and the other side has a similar side. However, acute interstitial pneumonia reported in the past because of the direct contrast to the literature remains a difficult Just for the record. Therefore, this issue should be identified through discussions with experts.

2011/05/11 18:16 Discovery

Centers for Disease Control recently as the cause of an unknown lung disease admitted to large hospitals in Seoul from 6 patients with this disease pathogens in test scores had a pandemic that had found no signs said 11 days.

CDC's name for what these 'acute interstitial pneumonia concluded that the interim.

According to the Centers for Disease Control pathogen test results of patients wherein patients 'adenovirus type 53' has been disconnected. The other 5 were isolated from residual pathogens.

Isolated adenoviruses cause pneumonia, but this pattern differs from that of patients have shown disease association between disease judged to be less that the KCDC said.

In this regard, CDC official said, "In tests so far failed to identify the causes of diseases, and at the future of health care institutions and after an investigation and discussion going," said "additional outbreaks around the patient, nor immunity to the elderly at less similar cases are found circulating in the community may not be concluded that low. "he explained. The official "in existing lung thresher usually around 30% do not confirm the cause." He said.





Director of Infectious Disease Center for Disease Control yangbyeongguk the "mother from a concentration that caused significant concern is the situation." Said, "children or adults who had similar symptoms as long as the data from the focus on women is a disorder include difficult to view. "he said.

Anseokgija ccto@seoul.co.kr

http://translate.google.com/translate?h ... rmd%3Divns

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This is just an opportunistic infection. The same thing was seen in the SARS outbreak. Several different viruses were found in individual patients before the SARS coronovirus was identified.

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Although these infections produce severe lung disease and are H1N1, like Mexico, there appear to be major problems isolating the virus, which is concentrated in the lung. These failures may be contributing to delays in reporting, as well as significant under-reporting in South Korea and worldwide.

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http://www.chinadaily.com.cn/hqzx/2011- ... 502718.htm

Pregnant women flu rise to a "honeycomb lung" death trap, Seoul Hospital, fear the unknown virus

Consolidated foreign media reports on May 12, a hospital in Seoul, South Korea appears strange suspected disease caused by a virus, seven patients have been produced or all pregnant women about to give birth and now has a woman was killed and six people are hospitalized treatment.


Korea Center for Disease Control and Prevention said on May 10, a 36-year-old, pregnant women have been the day of 9 months in the early morning death of a general hospital in Seoul. The deceased April 8 Zengyin sick to the hospital, was diagnosed with tuberculosis. The three-day drug treatment is not effective, further deterioration of women's disease, was admitted to the ICU. Hospital surgery was carried out premature, so she received further treatment.


But after delivery, the patient of tuberculosis in a very short period of time to transition to pulmonary fibrosis, cerebral bleeding occurred at the same time, and ultimately death. The so-called pulmonary fibrosis is the proliferation of mesenchymal cells in the lung, a large amount of collagen and extracellular matrix, the normal structure of lung tissue is replaced by cystic cavity, to the late development of this disease will be presented throughout the honeycomb lung.

Even more alarmed that the hospital, the hospital's other six have been produced or the labor of pregnant women had the same symptoms.


South Korean officials said that at present can not be sure this is a virus, but can determine the speed of its spread seems unhappy. Korea Center for Disease Control and Prevention have been from the dead and six patients were extracted sample has not found cause of death unknown viruses. An official of the Centre, said: "DNA test samples need more time. We extracted samples from the dead is a common virus like influenza virus, but we need better understanding of what led to pulmonary fibrosis. "


The official said, "it is necessary to clarify whether this is a new variant of the virus. We will conduct further tests to determine the cause of this woman's real cause of death, but also by analyzing the remaining patients, including food and living environment Other factors that determine the causes of these symptoms. "


(Source: China Daily Letter Lin Editor: Sun Tian)

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