The first case of resistance to the antiviral Tamiflu (oseltamivir) from an influenza infection has been reported in Australia.
A 38-year West Australian man, who had previously received a kidney transplant, developed complications from the virus despite treatment with the antiviral, doctors treating him reported this week in the Medical Journal of Australia.
"After a 10-day course of oral oseltamivir for pandemic (H1N1) 2009 influenza infection, a renal transplant recipient developed rapid-onset severe primary viral pneumonia due to oseltamivir-resistant virus," the doctors wrote.
"Respiratory failure progressed despite high-dose oral oseltamivir, nebulised zanamivir (Relenza) and cessation of immunosuppressive medications, but his condition improved with intravenous zanamivir. He subsequently died of non-respiratory complications.
This is the first case....http://www.pharmacynews.com.au/article/ ... 09152.aspx